Invitrogen™ Phospho-Histone H4 (Tyr89) Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5105105

Catalog No. PIPA5105105

Description

Antibody detects endogenous levels of Histone H4 only when phosphorylated at Tyr89.

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H4 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6.

Specifications

• Antigen: Phospho-Histone H4 (Tyr89)
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: H4C1
• Gene Alias: BcDNA:RH52884; BUR5; CELE_T10C6.11; CG31611; CG3379; CG3379-PA; CG3379-PB; CG3379-PC; CG3379-PD; CG33869; CG33871; CG33873; CG33875; CG33877; CG33879; CG33881; CG33883; CG33885; CG33887; CG33889; CG33891; CG33893; CG33895; CG33897; CG33899; CG33901; CG33903; CG33905; CG33907; CG33909; Dmel\CG3379; Dmel_CG3379; F07B7.11; F07B7.4; F45F2.12; FBtr0082962; FO108; germinal histone H4; H1ft; H4; H4 clustered histone 11; H4 clustered histone 2; H4 histone family, member A; H4 histone family, member I; H4 histone family, member J; H4 histone family, member M; H4 histone family, member N; H4 histone, family 2; H4.1; H4/A; H4/B; H4/C; H4/D; H4/E; H4/G; H4/H; H4/I; H4/J; H4/K; H4/M; H4/N; H4/O; H4/p; H4-12; H4-16; H4-53; H4c1; H4C11; H4c12; H4C13; H4c14; H4C15; H4C2; H4c3; H4C4; H4C5; H4c6; H4c8; H4C9; H4f16; H4F2; H4FA; H4FB; H4FC; H4FD; H4FE; H4FG; H4FH; H4FI; H4FJ; H4FK; H4FM; H4FN; H4FO; H4ft; H4M; H4r; HHF1; HHF2; HHT1; HHT2; his-20; his-22; His4; his-4; His4:CG31611; His4:CG33869; His4:CG33871; His4:CG33873; His4:CG33875; His4:CG33877; His4:CG33879; His4:CG33881; His4:CG33883; His4:CG33885; His4:CG33887; His4:CG33889; His4:CG33891; His4:CG33893; His4:CG33895; His4:CG33897; His4:CG33899; His4:CG33901; His4:CG33903; His4:CG33905; His4:CG33907; His4:CG33909; His4-88CD; His4r; His4r-PA; His4r-PB; His4r-PC; His4r-PD; his-52; his-54; his-8; HIST1H46L2; HIST1H4A; hist1h4a.L; Hist1h4b; HIST1H4C; HIST1H4D; HIST1H4E; Hist1h4f; Hist1h4h; Hist1h4i; Hist1h4j; HIST1H4K; HIST1H4L; Hist1h4m; HIST2H4; Hist2h4a; HIST2H4B; Hist4; Hist4h4; histone 1, H4a; histone 1, H4b; histone 1, H4e; histone 1, H4i; histone 1, H4l; histone 2, H4; histone 2, H4a; Histone 4; Histone 4 family, member M; histone 4, H4; histone cluster 1, H4a; histone cluster 1, H4a L homeolog; histone cluster 1, H4b; histone cluster 1, H4e; histone cluster 1, H4i; histone cluster 1, H4-IV, germinal H4-like 2; histone cluster 1, H4-IV, germinal H4-like 2 (similar to human histone cluster 1, class H4 genes); histone cluster 2, H4; histone cluster 2, H4a; Histone Cluster 4; histone cluster 4, H4; histone family member; Histone H2B 2; Histone H3; histone H4; histone H4 replacement; histone H4.1; Histone H4A; histone IV, family 2; K06C4.12; K06C4.4; N2749; N2752; OGP; Osteogenic growth peptide; RH52884p; SIN2; T10C6.11; X04652; XELAEV_18001418mg; YBR009C; YBR010W; YBR0122; YBR0201; YNL030W; YNL031C
• Host Species: Rabbit
• Purification Method: Sequential Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 121504, 280691, 319158, 326619, 326620, 679983, 8294, 8359, 8363, 8366, 8367, 8370, 97122
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: P62803, P62805, P62806
• Gene Symbols: H4-16, H4C1, H4C11, H4C14, H4C2, H4C5, H4C9, HIST1H4A
• Immunogen: A synthesized peptide derived from human Histone H4(Accession P62805), corresponding to amino acid residues around phosphorylated Tyr89.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat, Bovine, Pig
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov