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Invitrogen™ Phospho-Histone H4 (Tyr72) Polyclonal Antibody
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Catalog No. PIPA5143708
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PIPA5143708 100 μL
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Catalog No. PIPA5143708 Supplier Invitrogen™ Supplier No. PA5143708
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Description

Rabbit Polyclonal Antibody

The antibody was cross adsorbed to unphosphorylated histone H4 (Tyr-72) peptide before affinity purification using phospho-histone H4 (Tyr-72) peptide. This antibody antibody detects a 10 kDa* protein on SDS-PAGE immunoblots of human PC3 and A431 cells. This reactivity is not observed after alkaline phosphatase dephosphorylation of histone H4.

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H4 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Phospho-Histone H4 (Tyr72)
Applications Western Blot
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 1mg/mL BSA, 50% glycerol and 0.05% sodium azide
Gene H4C1
Gene Accession No. P62804, P62805, P62806
Gene Alias BcDNA:RH52884; BUR5; CELE_T10C6.11; CG31611; CG3379; CG3379-PA; CG3379-PB; CG3379-PC; CG3379-PD; CG33869; CG33871; CG33873; CG33875; CG33877; CG33879; CG33881; CG33883; CG33885; CG33887; CG33889; CG33891; CG33893; CG33895; CG33897; CG33899; CG33901; CG33903; CG33905; CG33907; CG33909; Dmel\CG3379; Dmel_CG3379; F07B7.11; F07B7.4; F45F2.12; FBtr0082962; FO108; germinal histone H4; H1ft; H4; H4 clustered histone 11; H4 clustered histone 2; H4 histone family, member A; H4 histone family, member I; H4 histone family, member J; H4 histone family, member M; H4 histone family, member N; H4 histone, family 2; H4.1; H4/A; H4/B; H4/C; H4/D; H4/E; H4/G; H4/H; H4/I; H4/J; H4/K; H4/M; H4/N; H4/O; H4/p; H4-12; H4-16; H4-53; H4c1; H4C11; H4c12; H4C13; H4c14; H4C15; H4C2; H4c3; H4C4; H4C5; H4c6; H4c8; H4C9; H4f16; H4F2; H4FA; H4FB; H4FC; H4FD; H4FE; H4FG; H4FH; H4FI; H4FJ; H4FK; H4FM; H4FN; H4FO; H4ft; H4M; H4r; HHF1; HHF2; HHT1; HHT2; his-20; his-22; His4; his-4; His4:CG31611; His4:CG33869; His4:CG33871; His4:CG33873; His4:CG33875; His4:CG33877; His4:CG33879; His4:CG33881; His4:CG33883; His4:CG33885; His4:CG33887; His4:CG33889; His4:CG33891; His4:CG33893; His4:CG33895; His4:CG33897; His4:CG33899; His4:CG33901; His4:CG33903; His4:CG33905; His4:CG33907; His4:CG33909; His4-88CD; His4r; His4r-PA; His4r-PB; His4r-PC; His4r-PD; his-52; his-54; his-8; HIST1H46L2; HIST1H4A; hist1h4a.L; Hist1h4b; HIST1H4C; HIST1H4D; HIST1H4E; Hist1h4f; Hist1h4h; Hist1h4i; Hist1h4j; HIST1H4K; HIST1H4L; Hist1h4m; HIST2H4; Hist2h4a; HIST2H4B; Hist4; Hist4h4; histone 1, H4a; histone 1, H4b; histone 1, H4e; histone 1, H4i; histone 1, H4l; histone 2, H4; histone 2, H4a; Histone 4; Histone 4 family, member M; histone 4, H4; histone cluster 1, H4a; histone cluster 1, H4a L homeolog; histone cluster 1, H4b; histone cluster 1, H4e; histone cluster 1, H4i; histone cluster 1, H4-IV, germinal H4-like 2; histone cluster 1, H4-IV, germinal H4-like 2 (similar to human histone cluster 1, class H4 genes); histone cluster 2, H4; histone cluster 2, H4a; Histone Cluster 4; histone cluster 4, H4; histone family member; Histone H2B 2; Histone H3; histone H4; histone H4 replacement; histone H4.1; Histone H4A; histone IV, family 2; K06C4.12; K06C4.4; N2749; N2752; OGP; Osteogenic growth peptide; RH52884p; SIN2; T10C6.11; X04652; XELAEV_18001418mg; YBR009C; YBR010W; YBR0122; YBR0201; YNL030W; YNL031C
Gene Symbols H4-16, H4C1, H4C11, H4C14, H4C2, H4C5, H4C9, HIST1H4A
Host Species Rabbit
Immunogen Phospho-Histone H4 (Tyr-72) synthetic peptide (coupled to carrier) corresponding to amino acids surrounding Tyr-72 in human histone H4. This site is well conserved in rat and mouse histone H4, but the site is not found in other histone family members.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 121504, 319158, 326619, 326620, 679983, 8294, 8359, 8363, 8366, 8367, 8370, 97122
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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