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Invitrogen™ Phospho-HMGCR (Ser872) Polyclonal Antibody
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Catalog No. PIPA5114581
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100 μL
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PIPA5114581 100 μL
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Catalog No. PIPA5114581 Supplier Invitrogen™ Supplier No. PA5114581
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of HMGCR only when phosphorylated at Ser872.

3-Hydroxy-3-Methylglutaryl-CoA Reductase (HMGCR) is a key enzyme in the mevalonate pathway, which is critical for the biosynthesis of cholesterol and other isoprenoids. HMGCR catalyzes the conversion of HMG-CoA to mevalonate, a rate-limiting step in the production of cholesterol. Due to its central role in cholesterol synthesis, HMGCR is a primary target for statin drugs, which are used to lower cholesterol levels and reduce the risk of cardiovascular disease.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Phospho-HMGCR (Ser872)
Applications Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide
Gene HMGCR
Gene Accession No. P04035, P51639, Q01237
Gene Alias 3H3M; 3-hydroxy-3-methylglutaryl CoA reductase (NADPH); 3-hydroxy-3-methylglutaryl-CoA reductase; 3-hydroxy-3-methylglutaryl-Coenzyme A reductase; HMDH; HMG CoA reductase; HMG CoAR; HMG-CoA reductase; HMG-CoAR; HMGCR; hydroxymethylglutaryl-CoA reductase; LDLCQ3; MGC103269; Red
Gene Symbols HMGCR
Host Species Rabbit
Immunogen A synthesized peptide derived from human HMGCR around the phosphorylation site of Ser872.
Purification Method sequential chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 15357, 25675, 3156
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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