Invitrogen™ Phospho-hnRNP K (Ser284) Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA536811

Catalog No. PIPA536811

Description

This antibody detects endogenous protein at a molecular weight of 51 kDa. Purity is >95% by SDS-PAGE.

This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene is located in the nucleoplasm and has three repeats of KH domains that binds to RNAs. It is distinct among other hnRNP proteins in its binding preference; it binds tenaciously to poly(C). This protein is also thought to have a role during cell cycle progression. Several alternatively spliced transcript variants have been described for this gene, however, not all of them are fully characterized.

Specifications

• Antigen: Phospho-hnRNP K (Ser284)
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: HNRNPK
• Gene Alias: AUKS; CSBP; dC stretch-binding protein; dC-stretch binding protein; FLJ41122; heterogeneous nuclear ribonucleoprotein K; heterogeneous nuclear ribonucleoprotein K S homeolog; hnRNP K; Hnrnpk; hnRNP-K protein; hnrnpk.S; hnrpk; KBBP; NOVA; RP11-575L7.1; transformation upregulated nuclear protein; Transformation up-regulated nuclear protein; TUNP; XELAEV_18010151mg
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 117282, 15387, 3190
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 15mM sodium azide; pH 7.2
• Gene Accession No.: P61978, P61979, P61980
• Gene Symbols: HNRNPK
• Immunogen: Synthetic phosphopeptide derived from human hnRNP K around the phosphorylation site of Serine 284.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG