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Invitrogen™ Phospho-HSP27 (Ser78) Polyclonal Antibody
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Catalog No. PIPA5114583
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PIPA5114583 100 μL
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Catalog No. PIPA5114583 Supplier Invitrogen™ Supplier No. PA5114583
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of HSP27 only when phosphorylated at Serine 78.

In response to adverse changes in their environment, cells from many organisms increase the expression of a class of proteins referred to as heat shock or stress proteins. HSPB1 (heat shock protein beta-1 or HSP27) is a small heat shock protein which functions as a molecular chaperone that maintains denatured proteins in a folding-competent state. It plays a role in stress resistance and actin organization. Through its molecular chaperone activity, HSP27 regulates numerous biological processes including the phosphorylation and the axonal transport of neurofilament proteins. Mutations in the gene can result in Charcot-Marie-Tooth disease 2F and Neuronopathy distal hereditary motor 2B.
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Specifications

Antigen Phospho-HSP27 (Ser78)
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide
Gene HSPB1
Gene Accession No. P04792
Gene Alias 27kDa; 28 kDa heat shock protein; CMT2F; DKFZp586P1322; epididymis secretory protein Li 102; estrogen-regulated 24 kDa protein; Growth-related 25 kDa protein; heat shock 25 kDa protein; Heat shock 27 kDa protein; heat shock 27kD protein 1; heat shock 27kDa protein 1; Heat shock protein; heat shock protein 1; heat shock protein 27 kDa beta-1; heat shock protein B1; heat shock protein beta-1; heat shock protein family B (small) member 1; heat shock protein, 25 kDa; heat-shock protein; HEL-S-102; HMN2B; HS; HS.76067; HSP; HSP 25; HSP 27; Hsp25; HSP27; HSP28; HSPB1; p25; Phospho-HSP 27; SRP27; Stress-responsive protein 27; truncated hsp25
Gene Symbols HSPB1
Host Species Rabbit
Immunogen A synthesized peptide derived from human HSPB1(Accession P04792), corresponding to amino acid residues around phosphorylated Ser78.
Purification Method Sequential Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 3315
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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