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Invitrogen™ Phospho-IKK alpha (Ser176) Polyclonal Antibody

Rabbit Polyclonal Antibody
Supplier: Invitrogen™ PA5121282
This item is not returnable.
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Description
Positive test controls include: HeLa, C6. The target is usually found in the following locations: Cytoplasm, Nucleus. Immunogen sequence: QGSLC.
CHUK (IKK alpha) is a serine/threonine kinase involved in signal transduction and cellular communication. It belongs to the cytokine activated protein complex that is an inhibitor of the NF-kappa B complex. IKK alpha along with IKK beta and a regulatory protein NEMO (IKK gamma) phosphorylates IkB proteins which targets the later for ubiquitin mediated degradation. It is involved with several cellular processes with extensive studies on its role in inflammation and cell survival.
Specifications
Phospho-IKK alpha (Ser176) | |
Polyclonal | |
Unconjugated | |
CHUK | |
AI256658; CHUK; Chuk1; component of inhibitor of nuclear factor kappa B kinase complex; conserved helix-loop-helix ubiquitous kinase; EC 2.7.11.10; Fbx24; Fbxo24; FLJ40509; I kappa B kinase 1; i kappa-B kinase alpha; ikappaB kinase; I-kappa-B kinase 1; I-kappa-B kinase 2; IkappaB kinase alpha; I-kappa-B kinase alpha; I-kappa-B kinase-alpha; IkB kinase alpha subunit; IkB kinase-alpha; ikBKA; IKBKB; IKK alpha; IKK1; IKK2; Ikka; IKK-A; IKK-a kinase; IKK-alpha; IKKB; IKK-B; IKK-beta; Inhibitor of nuclear factor kappa-B kinase subunit alpha; kinase beta; MGC131801; NFKBIKA; NFKBIKB; Nuclear factor NFkappaB inhibitor kinase alpha; Nuclear factor NF-kappa-B inhibitor kinase alpha; TCF16; TCF-16; Transcription factor 16 | |
Rabbit | |
Affinity Chromatography | |
RUO | |
1147, 12675, 309361 | |
-20°C, Avoid Freeze/Thaw Cycles | |
Liquid |
ELISA, Western Blot | |
0.7 mg/mL | |
PBS with 50% glycerol and 0.09% sodium azide; pH 7.3 | |
O15111, Q60680 | |
CHUK | |
A synthetic phosphorylated peptide around S176 of human IKK alpha (NP_0012693). | |
100 μL | |
Primary | |
Human, Mouse, Rat | |
Antibody | |
IgG |
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