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Phospho-IKKi (Ser172) Rabbit anti-Human, Polyclonal, Bioss
SDP

Catalog No. 501988660
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50-198-8660 100 μL
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Catalog No. 50-198-8660 Supplier Bioss Supplier No. BS8583R
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Description

Rabbit Polyclonal Antibody

Nuclear factor kappa B (NF-kappa-B) is a ubiquitous transcription factor and an essential mediator of gene expression during activation of immune and inflammatory responses. NF-kappa-B mediates the expression of a great variety of genes in response to extracellular stimuli. NF-kappa-B is associated with Ikappa-B proteins in the cell cytoplasm, which inhibit NF-kappa-B activity. Ikappa-B is phosphorylated by Ikappa-B kinase (IKK) complex that contains IKK-a, IKK-b, and IKK-gamma. A novel molecule in the IKK complex was recently identified and designated IKK-iota/IKK-i. IKK epsilon is required for the activation of NF-kappa-B by PMA and T cell receptors but not by TNF-a and IL-1. IKK-iota/IKK-i message is expressed in a variety of tissues and is inducible by TNF-a, IL-1, and LPS.

Specifications

Antigen Phospho-IKKi (Ser172)
Applications Flow Cytometry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 μg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene IKBKE
Gene Accession No. Q14164
Gene Alias AW558201; I-kappa-B kinase epsilon; IKBKE; Ikke; IKK-E; IKKepsilon; IKK-epsilon; Ikki; IKK-i; IKK-related kinase epsilon; Inducible I kappa-B kinase; inducible IkappaB kinase; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon; inhibitor of kappaB kinase epsilon; Inhibitor of nuclear factor kappa-B kinase subunit epsilon; KIAA0151; RP11-534L20.1
Gene Symbols IKBKE
Host Species Rabbit
Immunogen KLH conjugated synstic phosphopeptide derived from human IKKi/IKKE around the phosphorylation site of Ser172 [FV (p-S)VY].
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 9641
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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