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Invitrogen™ Phospho-ILK (Ser343) Polyclonal Antibody
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Catalog No. PIPA599568
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100 μL
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PIPA599568 100 μL
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Catalog No. PIPA599568 Supplier Invitrogen™ Supplier No. PA599568
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of ILK only when phosphorylated at Ser343.

Transduction of extracellular matrix signals through integrins influences intracellular and extracellular functions, and appears to require interaction of integrin cytoplasmic domains with cellular proteins. Integrin-linked kinase (ILK), interacts with the cytoplasmic domain of beta-1 integrin. This gene encodes a serine/threonine protein kinase with 4 ankyrin-like repeats, which associates with the cytoplasmic domain of beta integrins and acts as a proximal receptor kinase regulating integrin-mediated signal transduction. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Phospho-ILK (Ser343)
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene ILK
Gene Accession No. O55222, Q13418, Q99J82
Gene Alias 59 kDa serine/threonine-protein kinase; AA511515; epididymis secretory protein Li 28; ESTM24; HEL-S-28; ILK; ILK1; ILK-1; ILK2; ILK-2; integrin binding protein kinase; Integrin linked ILK; integrin linked kinase; integrin-linked kinase; integrin-linked kinase-2; integrin-linked protein kinase; loc; lost-contact; main squeeze; msq; P59; p59ILK; zgc:65842; zilk
Gene Symbols ILK
Host Species Rabbit
Immunogen A synthesized peptide derived from human ILK(Accession Q13418), corresponding to amino acid residues around phosphorylated Ser343.
Purification Method Sequential chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 16202, 170922, 3611
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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