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Invitrogen™ Phospho-INCENP (Thr59) Polyclonal Antibody
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Catalog No. PIPA5106183
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PIPA5106183 100 μL
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Catalog No. PIPA5106183 Supplier Invitrogen™ Supplier No. PA5106183
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Rabbit Polyclonal Antibody

Antibody detects endogenous levels of INCENP only when phosphorylated at Thr59.

Chromosomal passenger proteins are members of a group of proteins that move from centromeres to the spindle midzone during mitosis. INCENP (Inner Centromere Protein) is a chromosomal passenger protein with an essential role in mitosis and meiosis. It is a complex highly basic multidomain protein that is dynamically translocated from metaphase chromosomes to the spindle midzone during or just prior to anaphase. Some INCENP transfers to the equatorial cortex before formation of the cleavage furrow. Ultimately, it is discarded in the midbody at the completion of cytokinesis.
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Specifications

Antigen Phospho-INCENP (Thr59)
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Incenp
Gene Accession No. Q9NQS7, Q9WU62
Gene Alias 2700067E22Rik; AU019509; binds and activates aurora-B and -C in vivo and in vitro; C130081E20; C77457; chromosomal passenger protein; Incenp; Inner centromere protein; inner centromere protein antigens 135/155kDa; inner centromere protein INCENP
Gene Symbols Incenp
Host Species Rabbit
Immunogen A synthesized peptide derived from human INCENP(Accession Q9NQS7), corresponding to amino acid residues around phosphorylated Thr59.
Purification Method Sequential chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 16319, 293733, 3619
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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