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Invitrogen™ Phospho-IRAK-M (Ser510) Polyclonal Antibody
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Catalog No. PIPA5105121
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Catalog No. Quantity
PIPA5105121 100 μL
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Catalog No. PIPA5105121 Supplier Invitrogen™ Supplier No. PA5105121
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of IRAK3 only when phosphorylated at Ser510.

IRAK3 serine/threonine kinase or interleukin-1 receptor-associated kinase 3 is a member of the interleukin-1 receptor-associated kinase protein family which are essential components of the Toll/IL-R immune signal transduction pathways. IRAK3 is primarily expressed in monocytes and macrophages and functions as a negative regulator of Toll-like receptor signaling. IRAK3 mediates critical aspects of innate immunity that result in an immunocompromised state during sepsis. Mutations in IRAK3 are associated with a susceptibility to asthma.
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Specifications

Antigen Phospho-IRAK-M (Ser510)
Applications Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene IRAK3
Gene Accession No. Q8K4B2, Q9Y616
Gene Alias 4833428C18Rik; AI563835; ASRT5; FLJ13601; IL-1 receptor-associated kinase M; interleukin 1 receptor associated kinase 3; interleukin-1 receptor-associated kinase 3; IRAK3; IRAK-3; IRAKM; IRAK-M
Gene Symbols IRAK3
Host Species Rabbit
Immunogen A synthesized peptide derived from human IRAK3(Accession Q9Y616), corresponding to amino acid residues around phosphorylated Ser510.
Purification Method Sequential Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 11213, 314870, 73914
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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