Phospho-ITGB4 (Tyr1494) Rabbit anti-Human, Polyclonal, Bioss

Catalog No.	Quantity
50-198-6577	100 μL

Catalog No. 50-198-6577 Supplier Bioss Supplier No. BS5455R

Description

Rabbit Polyclonal Antibody

Integrins are heterodimers comprised of alpha and beta subunits, that are noncovalently associated transmembrane glycoprotein receptors. Different combinations of alpha and beta polypeptides form complexes that vary in their ligand-binding specificities. Integrins mediate cell-matrix or cell-cell adhesion, and transduced signals that regulate gene expression and cell growth. This gene encodes the integrin beta 4 subunit, a receptor for the laminins. This subunit tends to associate with alpha 6 subunit and is likely to play a pivotal role in the biology of invasive carcinoma. Mutations in this gene are associated with epidermolysis bullosa with pyloric atresia. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Specifications

• Antigen: Phospho-ITGB4 (Tyr1494)
• Applications: Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
• Classification: Polyclonal
• Concentration: 1 μg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
• Gene: ITGB4
• Gene Accession No.: P16144
• Gene Alias: AA407042; C230078O20; CD antigen CD104; CD104; CD104 antigen; GP150; integrin beta 4; Integrin beta-4; integrin subunit beta 4; integrin, beta 4; ITGB4
• Gene Symbols: ITGB4
• Host Species: Rabbit
• Immunogen: KLH conjugated synthetic phosphopeptide derived from mouse ITGB4 around the phosphorylation site of Tyr1494.
• Purification Method: Protein A
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 3691
• Target Species: Human
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG