Invitrogen™ Phospho-JunD (Ser255) Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5104821

Catalog No. PIPA5104821

Description

Antibody detects endogenous levels of JunD only when phosphorylated at Serine 255.

JunD is a transcription factor which is coded by JunD gene. JunD transcriptional activity is modulated by phosphorylation in response to cellular stress via the c-Jun N terminal kinase (JNK)/Stress-Activated Protein Kinase (SAPK) family of protein kinase. Jun proteins are capable of forming dimers with Fos, ATF and CREB family transcription factors to form the AP-1 complex that differentially regulates a variety of target genes involved in cellular growth, proliferation, differentiation and apoptosis. Also, JunD plays an important role in metabolism via modulation of IGF-1 signaling pathway.

Specifications

• Antigen: Phospho-JunD (Ser255)
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: JUND
• Gene Alias: activator protein 1; AP1; AP-1; JUN D; jun D proto-oncogene; Jun proto-oncogene related gene d; Jun proto-oncogene related gene d1; Jund; Jun-d; JunD proto-oncogene, AP-1 transcription factor subunit; Jund1; JunD-FL isoform; Oncogene Jun-D; Transcription factor jun-D
• Host Species: Rabbit
• Purification Method: sequential chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 16478, 24518, 3727
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: P15066, P17535, P52909
• Gene Symbols: JUND
• Immunogen: A synthesized peptide derived from human JUND(Accession P17535), corresponding to amino acid residues around phosphorylated Ser255.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov