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Invitrogen™ Phospho-JunD (Ser255) Recombinant Rabbit Monoclonal Antibody (JJ08-21)
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Catalog No. PIMA532444
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PIMA532444 100 μL
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Catalog No. PIMA532444 Supplier Invitrogen™ Supplier No. MA532444
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Description

Rabbit Recombinant Monoclonal Antibody

Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.

JunD is a transcription factor which is coded by JunD gene. JunD transcriptional activity is modulated by phosphorylation in response to cellular stress via the c-Jun N terminal kinase (JNK)/Stress-Activated Protein Kinase (SAPK) family of protein kinase. Jun proteins are capable of forming dimers with Fos, ATF and CREB family transcription factors to form the AP-1 complex that differentially regulates a variety of target genes involved in cellular growth, proliferation, differentiation and apoptosis. Also, JunD plays an important role in metabolism via modulation of IGF-1 signaling pathway.
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Specifications

Antigen Phospho-JunD (Ser255)
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry, Western Blot
Classification Recombinant Monoclonal
Clone JJ08-21
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide; pH 7.4
Gene JUND
Gene Accession No. P15066, P17535, P52909
Gene Alias activator protein 1; AP1; AP-1; JUN D; jun D proto-oncogene; Jun proto-oncogene related gene d; Jun proto-oncogene related gene d1; Jund; Jun-d; JunD proto-oncogene, AP-1 transcription factor subunit; Jund1; JunD-FL isoform; Oncogene Jun-D; Transcription factor jun-D
Gene Symbols JUND
Host Species Rabbit
Immunogen Synthetic phospho-peptide corresponding to residues surrounding Ser255 of Human JunD aa 251-270.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 16478, 24518, 3727
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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