Invitrogen™ Phospho-KIF20A (Tyr869) Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5105438

Catalog No. PIPA5105438

Description

Antibody detects endogenous levels of KIF20A only when phosphorylated at Tyr869.

Mitotic kinesin required for chromosome passenger complex (CPC)-mediated cytokinesis. Following phosphorylation by PLK1, involved in recruitment of PLK1 to the central spindle. Interacts with guanosine triphosphate (GTP)-bound forms of RAB6A and RAB6B. May act as a motor required for the retrograde RAB6 regulated transport of Golgi membranes and associated vesicles along microtubules. Has a microtubule plus end-directed motility. [UniProt].

Specifications

• Antigen: Phospho-KIF20A (Tyr869)
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: KIF20A
• Gene Alias: AA415432; GG10_2; KIF20A; kinesin family member 20A; kinesin-like protein 174; Kinesin-like protein KIF20A; mitotic kinesin-like protein 2; MKlp2; RAB6 interacting, kinesin-like (rabkinesin6); rab6-interacting kinesin-like protein; RAB6KIFL; Rabkinesin-6
• Host Species: Rabbit
• Purification Method: Sequential Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 10112, 19348, 361308
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: O95235, P97329
• Gene Symbols: KIF20A
• Immunogen: A synthesized peptide derived from human KIF20A(Accession O95235), corresponding to amino acid residues around phosphorylated Tyr869.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov