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Invitrogen™ Phospho-Kinesin 5B (Ser154) Polyclonal Antibody
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Catalog No. PIPA5105705
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PIPA5105705 100 μL
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Catalog No. PIPA5105705 Supplier Invitrogen™ Supplier No. PA5105705
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of KIF5B only when phosphorylated at Ser154.

Microtubule-dependent motor required for normal distribution of mitochondria and lysosomes. Can induce formation of neurite-like membrane protrusions in non-neuronal cells in a ZFYVE27-dependent manner. Regulates centrosome and nuclear positioning during mitotic entry. During the G2 phase of the cell cycle in a BICD2-dependent manner, antagonizes dynein function and drives the separation of nuclei and centrosomes. Required for anterograde axonal transportation of MAPK8IP3/JIP3 which is essential for MAPK8IP3/JIP3 function in axon elongation.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Phospho-Kinesin 5B (Ser154)
Applications Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene KIF5B
Gene Accession No. P33176, Q2PQA9, Q61768
Gene Alias AL022807; Conventional kinesin heavy chain; EMBL:ABC25059.1}; epididymis secretory protein Li 61; HEL-S-61; Khc; Khcs; KIF5A; KIF5B; kif5b {ECO:0000312; kinesin 1 (110-120kD); kinesin family member 5A; kinesin family member 5B; kinesin heavy chain; kinesin heavy chain member 5B, ubiquitous; kinesin-1 heavy chain; KINH; KNS; Kns1; ubiquitous kinesin heavy chain; UKHC; U-KHC; Unknown (protein for IMAGE:7944745)
Gene Symbols KIF5B
Host Species Rabbit
Immunogen A synthesized peptide derived from human KIF5B(Accession P33176), corresponding to amino acid residues around phosphorylated Ser154.
Purification Method Sequential chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 117550, 16573, 3799
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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