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Invitrogen™ Phospho-KISS1R (Ser368) Polyclonal Antibody
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Catalog No. PIPA5105314
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PIPA5105314 100 μL
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Catalog No. PIPA5105314 Supplier Invitrogen™ Supplier No. PA5105314
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of KISS1R only when phosphorylated at Ser368.

GCPR54 is a galanin-like G protein coupled receptor that binds metastin, a peptide encoded by the metastasis suppressor gene KISS1. The tissue distribution of the protein suggests that it is involved in the regulation of endocrine function, and this is supported by the finding that it appears to play a role in the onset of puberty. GPR54 has been reported in various human brain regions, placenta, pancreas, and spinal cord, and at lower levels in spleen, peripheral blood leukocytes, testis, lymph node, thymus, small intestine, stomach, lung, and kidney. The receptor is also abundant in tumor tissues. In rat, GPR54 is expressed in liver, intestine, and in the pons, midbrain, thalamus, hypothalamus, hippocampus, amygdala, cortex (including frontal), and striatum. ESTs have been isolated from normal placenta and kidney cancer libraries.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Phospho-KISS1R (Ser368)
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene KISS1R
Gene Accession No. Q91V45, Q924U1, Q969F8
Gene Alias AXOR12; CPPB1; G protein-coupled receptor 54; Gpr54; G-protein coupled receptor 54; G-protein coupled receptor OT7T175; HH8; HOT7T175; Hypogonadotropin-1; kiSS-; KiSS-1; KISS1 receptor; kiSS-1 receptor; KISS1R; KiSS-1R; Kisspeptins receptor; metastin receptor; mOT7T175; orphan G protein-coupled receptor 54; orphan G protein-coupled receptor GPR54; rOT7T175
Gene Symbols KISS1R
Host Species Rabbit
Immunogen A synthesized peptide derived from human KISS1R(Accession Q969F8), corresponding to amino acid residues around phosphorylated Ser368.
Purification Method Sequential chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 114229, 78976, 84634
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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