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Invitrogen™ Phospho-KLF4 (Ser254) Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5104680

Catalog No. PIPA5104680


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Description

Description

Antibody detects endogenous levels of KLF4 only when phosphorylated at Ser254.

Kruppel like factor 4 (KLF4) protein is encoded by the KLF4 gene located on chromosome 9 in humans. It is also known as gut-enriched Kruppel-like factor (GKLF) or epithelial zinc-finger protein (EZF) and belongs to a family of conserved Kruppel-like factor family of DNA binding zinc finger transcription factors. KLF4 exerts its functional relevance across varied cellular pathways. As one of the four Yamanaka factors, it plays a key role in reprogramming differentiated cells into pluripotent stem cells. Most studies have focused on its specific role in endothelial cell signaling, adipogenesis, differentiation, embryogenesis and cell cycle control. Localization plays an important role in the biological significance of this protein wherein nuclear localization is associated with its function as an oncogene and cytosolic localization with tumor suppression specific effect.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

Phospho-KLF4 (Ser254)
Polyclonal
Unconjugated
KLF4
endothelial Kruppel-like zinc finger protein; epithelial zinc finger protein EZF; Ezf; Gklf; gut Kruppel-like factor; gut-enriched krueppel-like factor; high mobility group nucleosomal binding domain 3; high mobility group nucleosome-binding domain-containing protein 3; HMGN3; KLF4; Krueppel-like factor 4; Kruppel like factor 4; Kruppel-like factor 4 (Gut enriched kruppel-like factor) (Epithelial zinc-finger protein EZF); Kruppel-like factor 4 (gut); PNAS-24; PNAS-25; RP11-150J11.1; thyroid hormone receptor interacting protein 7; Thyroid receptor-interacting protein 7; TR-interacting protein 7; TRIP7; Zie
Rabbit
Sequential chromatography
RUO
114505, 16600, 9314
-20°C
Liquid
Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
1 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
O43474, Q60793
KLF4
A synthesized peptide derived from human KLF4(Accession O43474), corresponding to amino acid residues around phosphorylated Ser254.
100 μL
Primary
Human, Mouse, Rat
Antibody
IgG
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