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Invitrogen™ Phospho-LAT (Tyr171) Polyclonal Antibody
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Catalog No. PIPA597408
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100 μL
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PIPA597408 100 μL
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Catalog No. PIPA597408 Supplier Invitrogen™ Supplier No. PA597408
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: DDYVN; Positive Samples: Jurkat; Cellular Location: Cell membrane, Single-pass type III membrane protein.

LAT (Linker for Activation of T cells) is a 36-38 kDa double-palmitoylated transmembrane adaptor protein expressed by T cells, pre-B cells, NK cells, mast cells and platelets. After immunoreceptor triggering, LAT becomes multiply tyrosine-phosphorylated by Syk-, Src-, or Tec-family kinases, providing docking sites for downstream signaling molecules. LAT is essential for TCR-dependent T cell- and FcepsilonRI-dependent mast cell activation, as well as for maturation of early thymocytes. It is also involved in NK cell signaling and platelet activation.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Phospho-LAT (Tyr171)
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 0.37 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
Gene LAT
Gene Accession No. O43561
Gene Alias 36 kDa phospho-tyrosine adapter protein; 36 kDa phospho-tyrosine adaptor protein; Lat; LAT1; linker for activation of T cells; linker for activation of T cells, transmembrane adaptor; linker for activation of T-cells; linker for activation of T-cells family member 1; linker protein; p36-38; pp36
Gene Symbols LAT
Host Species Rabbit
Immunogen Synthetic peptide
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 27040
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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