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Invitrogen™ Phospho-LAT (Tyr191) Recombinant Rabbit Monoclonal Antibody (2E4)
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Catalog No. PIMA533177
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100 μL
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PIMA533177 100 μL
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Catalog No. PIMA533177 Supplier Invitrogen™ Supplier No. MA533177
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Description

Rabbit Recombinant Monoclonal Antibody

Phospho-LAT (Tyr191) Recombinant Monoclonal Antibody for ELISA, ICC/IF, IHC (P), IP, Western Blot

LAT (Linker for Activation of T cells) is a 36-38 kDa double-palmitoylated transmembrane adaptor protein expressed by T cells, pre-B cells, NK cells, mast cells and platelets. After immunoreceptor triggering, LAT becomes multiply tyrosine-phosphorylated by Syk-, Src-, or Tec-family kinases, providing docking sites for downstream signaling molecules. LAT is essential for TCR-dependent T cell- and FcepsilonRI-dependent mast cell activation, as well as for maturation of early thymocytes. It is also involved in NK cell signaling and platelet activation.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Phospho-LAT (Tyr191)
Applications ELISA, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot, Immunocytochemistry, Western Blot
Classification Recombinant Monoclonal
Clone 2E4
Concentration 2.35 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol, 0.05% BSA and 0.02% sodium azide; pH 7.4
Gene LAT
Gene Accession No. O43561
Gene Alias 36 kDa phospho-tyrosine adapter protein; 36 kDa phospho-tyrosine adaptor protein; Lat; LAT1; linker for activation of T cells; linker for activation of T cells, transmembrane adaptor; linker for activation of T-cells; linker for activation of T-cells family member 1; linker protein; p36-38; pp36
Gene Symbols LAT
Host Species Rabbit
Immunogen A synthesized peptide derived from human Phospho-LAT (Y191).
Purification Method Antigen affinity chromatography, Protein G
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 27040
Target Species Human
Content And Storage -20°C or -80°C if preferred
Product Type Antibody
Form Liquid
Isotype IgG
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