Phospho-LAT (Tyr200) Rabbit anti-Human, Polyclonal, Bioss

Catalog No.	Quantity
50-198-0702	100 μL

Catalog No. 50-198-0702 Supplier Bioss Supplier No. BS10128R

Description

Rabbit Polyclonal Antibody

LAT (Linker for Activation of T cells) is a 36-38 kDa double-palmitoylated transmembrane adaptor protein expressed by T cells, pre-B cells, NK cells, mast cells and platelets. After immunoreceptor triggering, LAT becomes multiply tyrosine-phosphorylated by Syk-, Src-, or Tec-family kinases, providing docking sites for downstream signaling molecules. LAT is essential for TCR-dependent T cell- and FcepsilonRI-dependent mast cell activation, as well as for maturation of early thymocytes. It is also involved in NK cell signaling and platelet activation.

Specifications

• Antigen: Phospho-LAT (Tyr200)
• Applications: Flow Cytometry
• Classification: Polyclonal
• Concentration: 1 μg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
• Gene: LAT
• Gene Accession No.: O43561
• Gene Alias: 36 kDa phospho-tyrosine adapter protein; 36 kDa phospho-tyrosine adaptor protein; Lat; LAT1; linker for activation of T cells; linker for activation of T cells, transmembrane adaptor; linker for activation of T-cells; Linker for activation of T-cells family member 1; linker protein; p36-38; pp36
• Gene Symbols: LAT
• Host Species: Rabbit
• Immunogen: KLH conjugated synthetic phosphopeptide derived from human LAT around the phosphorylation site of Tyr200.
• Purification Method: Protein A
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 27040
• Target Species: Human
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG