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Invitrogen™ Phospho-LRP6 (Ser1490) Polyclonal Antibody
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Catalog No. PIPA5117266
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100 μL
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PIPA5117266 100 μL
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Catalog No. PIPA5117266 Supplier Invitrogen™ Supplier No. PA5117266
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Description

Rabbit Polyclonal Antibody

Positive Samples: HeLa Immunogen sequence: PPSPA.

LRP6 is essential for the Wnt/beta catenin signaling pathway, probably by acting as a coreceptor together with Frizzled for Wnt. It is a specific, high-affinity receptor for DKK1 and DKK2, but not DKK3. The interaction with DKK1 blocks LRP6-mediated Wnt/beta catenin signaling via LRP6 removal via Kremen proteins-mediated endocytosis.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Phospho-LRP6 (Ser1490)
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 0.429 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
Gene LRP6
Gene Accession No. O75581
Gene Alias ADCAD2; C030016K15Rik; Cd; crooked; FLJ90062; FLJ90421; Gw; LDL receptor related protein 6; low density lipoprotein receptor-related protein 6; low density lipoprotein receptor-related protein 6; low density lipoprotein-related protein 6; low density lipoprotein-related protein 6; low-density lipoprotein receptor-related protein 6; lpr6; LRP6; LRP-6; ska>m26Jus>; ska26; skax26; STHAG7
Gene Symbols LRP6
Host Species Rabbit
Immunogen A synthetic phosphorylated peptide around S1490 of human LRP6 (NP_0023272).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 4040
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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