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Invitrogen™ Phospho-LRRK2 (Ser910) Polyclonal Antibody
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Catalog No. PIPA5114598
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100 μL
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PIPA5114598 100 μL
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Catalog No. PIPA5114598 Supplier Invitrogen™ Supplier No. PA5114598
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of LRRK2 only when phosphorylated at Ser910.

LRRK2 is a multidomain protein that includes a kinase domain, a GTPase domain, and a leucine-rich repeat (LRR) domain. Mutations in LRRK2 have been associated with Parkinson's disease. LRRK2 is a member of the leucine-rich repeat kinase family and encodes a protein with an ankryin repeat region, a leucine-rich repeat domain, a kinase domain, a DFG-like motif, a RAS domain, a GTPase domain, a MLK-like domain, and a WD40 domain. The protein is present largely in the cytoplasm but also associates with the mitochondrial outer membrane.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Phospho-LRRK2 (Ser910)
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide
Gene LRRK2
Gene Accession No. Q5S007
Gene Alias 4921513O20Rik; 9330188B09Rik; augmented in rheumatoid arthritis 17; AURA17; AW561911; BC 300-268; cI-46; D630001M17Rik; DARDARIN; DKFZp434H2111; FLJ45829; Gm927; leucine rich repeat kinase 2; leucine-rich repeat kinase 2; leucine-rich repeat serine/threonine-protein kinase 2; LRR kinase 2; LRRK 2; Lrrk2; LRRK-2; PARK8; RIPK7; ROCO2
Gene Symbols LRRK2
Host Species Rabbit
Immunogen A synthesized peptide derived from human LRRK2 around the phosphorylation site of Ser910.
Purification Method sequential chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 120892
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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