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  6. Invitrogen™ Phospho-MAP2K4 (Ser257) Recombinant Rabbit Monoclonal Antibody (SEK1MKK4S257-C5), PE, Invitrogen™

Invitrogen™ Phospho-MAP2K4 (Ser257) Recombinant Rabbit Monoclonal Antibody (SEK1MKK4S257-C5), PE, Invitrogen™

Catalog No. PIMA537384
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PIMA537384 10 Tests
PIMA537138 100 Tests
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Catalog No. PIMA537384 Supplier Invitrogen™ Supplier No. MA537384
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Description

Rabbit Recombinant Monoclonal Antibody

MAP2K4 (MEK4) serine/threonine kinase (mitogen-activated protein kinase 4) MEK4 or MKK4 is a dual specificity kinase of the STE7 family that phosphorylates and activates JNK1 and -2 as well as p38. MAP2K4 preferentially phosphorylates the tyrosine residue of JNKs. MAP2K4 mediates a variety of physiological and pathophysiological processes such as responses to cellular stresses and inflammatory cytokines. MAP2K4 is important for carcinogenesis; a loss-off-function mutation in MAP2K4 was found in lung and pancreatic tumors. Conversely, a pro-oncogenic role was also found for MAP2K4.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Phospho-MAP2K4 (Ser257)
Applications Flow Cytometry
Classification Recombinant Monoclonal
Clone SEK1MKK4S257-C5
Conjugate PE
Formulation PBS with 0.20% BSA and 0.09% sodium azide
Gene MAP2K4
Gene Accession No. P45985, P47809
Gene Alias C-JUN N-terminal kinase kinase 1; dual specificity mitogen-activated protein kinase kinase 2; dual specificity mitogen-activated protein kinase kinase 4; dual specificity mitogen-activated protein kinase kinase 4; dual specificity mitogen-activated protein kinase kinase 4a; JNK kinase 1; JNK-activated kinase 1; JNK-activating kinase 1; JNKK; JNKK 1; JNKK1; MAP kinase activator 2; MAP kinase kinase 4; Map2k4; map2k4.L; map2k4a; map2k4-a; map2k4-b; MAP2K4delta; MAPK/ERK kinase 4; MAPKK 4; MAPKK4; MEK 4; MEK4; mitogen activated protein kinase kinase 4; mitogen activated protein kinase kinase 4, variant 1; mitogen-activated protein kinase kinase 4; mitogen-activated protein kinase kinase 4 L homeolog; mitogen-activated protein kinase kinase 4a; MKK4; mkk4a; MKK4A-l; PRKMK4; SAPK kinase 1; SAPK/ERK kinase 1; SAPK/Erk/kinase 1; SAPKK1; SAPKK-1; Sek1; Serk1; Skk1; Stress-activated protein kinase kinase 1; XELAEV_18044157mg; XMEK2; zgc:136500; zMKK4 protein
Gene Symbols MAP2K4
Host Species Rabbit
Immunogen A synthetic phospho-peptide corresponding to residues surrounding Ser257 of human phospho SEK1/MKK4.
Purification Method Protein A/G
Quantity 10 Tests
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 26398, 6416
Target Species Human, Mouse, Monkey
Content And Storage 4°C
Product Type Antibody
Form Liquid
Isotype IgG κ
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