Phospho-MAPKAPK2 (Thr222) Monoclonal Antibody (T.798.4), Invitrogen™

Rabbit Monoclonal Antibody

Supplier:  Thermo Scientific MA514894

Catalog No. PIMA514894

Description

It is not recommended to aliquot this antibody.

MAPKAPK2 mediates p38 and ERK signaling in vivo. It is known to be involved in many cellular processes including stress and inflammatory responses, nuclear export, gene expression regulation, and cell proliferation. MAPKAPK2 encodes a member of the Ser/Thr protein kinase family. MAPKAPK2 is regulated through direct phosphorylation by p38 MAP kinase. In conjunction with p38 MAP kinase, MAPKAPK2 is known to be involved in many cellular processes including stress and inflammatory responses, nuclear export, gene expression regulation and cell proliferation. Heat shock protein HSP27 was shown to be one of the substrates of this kinase in vivo. Two transcript variants encoding two different isoforms have been found for MAPKAPK2.

Specifications

• Antigen: Phospho-MAPKAPK2 (Thr222)
• Classification: Monoclonal
• Concentration: 270 μg/mL
• Formulation: 0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and <0.02% sodium azide; pH 7.5
• Gene Accession No.: P49137, P49138
• Gene Symbols: MAPKAPK2
• Immunogen: Synthetic phosphopeptide corresponding to residues surrounding pThr222 of human MAPKAPK-2
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Non-human Primate, Rat
• Product Type: Antibody
• Isotype: IgG

• Applications: Western Blot
• Clone: T.798.4
• Conjugate: Unconjugated
• Gene: MAPKAPK2
• Gene Alias: AA960234; MAP kinase-activated protein kinase 2; MAPK activated protein kinase 2; MAPK-activated protein kinase 2; MAPKAP kinase 2; Mapkapk2; MAPKAP-K2; MAPKAPK-2; mitogen-activated protein kinase-activated protein kinase 2; MK2; MK-2; Rps6kc1
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 17164, 289014, 9261
• Content And Storage: -20°C
• Form: Liquid