Invitrogen™ Phospho-MAPKAPK2 (Thr222) Monoclonal Antibody (T.798.4)

Catalog No.	Quantity
PIMA514894	100 μL

Catalog No. PIMA514894 Supplier Invitrogen™ Supplier No. MA514894

Description

Rabbit Monoclonal Antibody

It is not recommended to aliquot this antibody.

MAPKAPK2 mediates p38 and ERK signaling in vivo. It is known to be involved in many cellular processes including stress and inflammatory responses, nuclear export, gene expression regulation, and cell proliferation. MAPKAPK2 encodes a member of the Ser/Thr protein kinase family. MAPKAPK2 is regulated through direct phosphorylation by p38 MAP kinase. In conjunction with p38 MAP kinase, MAPKAPK2 is known to be involved in many cellular processes including stress and inflammatory responses, nuclear export, gene expression regulation and cell proliferation. Heat shock protein HSP27 was shown to be one of the substrates of this kinase in vivo. Two transcript variants encoding two different isoforms have been found for MAPKAPK2.

Specifications

• Antigen: Phospho-MAPKAPK2 (Thr222)
• Applications: Western Blot
• Classification: Monoclonal
• Clone: T.798.4
• Concentration: 270 μg/mL
• Conjugate: Unconjugated
• Formulation: 0.01M HEPES with 100 μg/mL BSA, 50% glycerol, 0.15M NaCl and <0.02% sodium azide; pH 7.5
• Gene: MAPKAPK2
• Gene Accession No.: P49137, P49138
• Gene Alias: AA960234; MAP kinase-activated protein kinase 2; MAPK activated protein kinase 2; MAPK-activated protein kinase 2; MAPKAP kinase 2; Mapkapk2; MAPKAP-K2; MAPKAPK-2; mitogen-activated protein kinase-activated protein kinase 2; MK2; MK-2; Rps6kc1
• Gene Symbols: MAPKAPK2
• Host Species: Rabbit
• Immunogen: Synthetic phosphopeptide corresponding to residues surrounding pThr222 of human MAPKAPK-2.
• Purification Method: Affinity Chromatography
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 17164, 289014, 9261
• Target Species: Human, Mouse, Rat, Monkey
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG