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Invitrogen™ Phospho-MARCKS (Ser158) Polyclonal Antibody
Rabbit Polyclonal Antibody
Supplier: Invitrogen™ PA5104861
Description
Antibody detects endogenous levels of MARCKS only when phosphorylated at Serine 159.
MARCKS is a substrate for protein kinase C. It is localized to the plasma membrane and is an actin filament crosslinking protein. Phosphorylation by protein kinase C or binding to calcium-calmodulin inhibits its association with actin and with the plasma membrane, leading to its presence in the cytoplasm. The protein is thought to be involved in cell motility, phagocytosis, membrane trafficking and mitogenesis.
Specifications
Phospho-MARCKS (Ser158) | |
Polyclonal | |
Unconjugated | |
MARCKS | |
80K protein; 80K-L; 80K-L protein; FLJ14368; FLJ90045; KINC; Macs; MARCKS; MARCS; myristoylated alanine rich protein kinase C substrate; myristoylated alanine-rich C-kinase substrate; Myristoylated alanine-rich protein kinase C substrate; myristoylated alanine-rich protein kinase C substrate (MARCKS, 80K-L); phosphomyristin; PKCSL; PRKCSL; protein kinase C substrate 80 kDa protein; protein kinase C substrate, 80 kDa protein, light chain | |
Rabbit | |
Sequential Chromatography | |
RUO | |
17118, 25603, 4082 | |
-20°C | |
Liquid |
Western Blot | |
1 mg/mL | |
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4 | |
P26645, P29966, P30009 | |
MARCKS | |
A synthesized peptide derived from human MARCKS(Accession P29966), corresponding to amino acid residues around phosphorylated Ser159. | |
100 μL | |
Primary | |
Human, Mouse, Rat | |
Antibody | |
IgG |
Safety and Handling
WARNING: Cancer - www.P65Warnings.ca.gov
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