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Phospho-MARCKS (Ser163) Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Supplier:  Thermo Scientific PA538139

Catalog No. PIPA538139


Description

Description

Myristoylated alanine-rich protein kinase C substrate (MARCKS), also designated 80K or 80K-L, has been identified as a major cellular substrate for protein kinase C. Human MARCKS is a 332 amino acid protein with a calculated molecular weight of 31.534 kDa; however, it has been shown to run at 80-87 kDa on Western blot. The plasma membrane bound protein dissociates from the membrane upon phosphorylation by various PKC isoforms. In NIH/3T3 fibroblasts, PKC alpha and PKC epsilon, but not PKC delta, are responsible for MARCKS phosphorylation. MARCKS has been found to bind calmodulin, Actin and Synapsin and is a filamentous (F) Actin crosslinking protein.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

Phospho-MARCKS (Ser163)
Polyclonal
Unconjugated
MARCKS
80K-L protein, MACS, MARCS, Myristoylated alanine-rich C-kinase substrate, PKCSL, PRKCSL, Protein kinase C substrate, 81 kDa protein, light chain
Rabbit
Antigen affinity chromatography
RUO
17118, 25603, 4082
-20°C
Liquid
Immunohistochemistry (Paraffin)
1 mg/mL
Dulbecco′s PBS with 150mM NaCl, 50% glycerol and 0.02% sodium azide; pH 7.4
P29966, P26645, P30009
MARCKS
A synthetic phosphopeptide derived from human MARCKS around the phosphorylation site of Ser162 (K-K-SP-F-K)
100 μg
Primary
Human, Mouse, Rat
Antibody
IgG
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