Invitrogen™ Phospho-MARK2 (Thr596) Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5105815

Catalog No. PIPA5105815

Description

Antibody detects endogenous levels of MARK2 only when phosphorylated at Thr596.

MARK2 is a serine/threonine protein kinase involved in the control of cell polarity and microtubule stability. Several cDNA clones have been isolated that encoded two isoforms of the human ser/thr protein kinase EMK1. These isoforms were characterized by the presence of a 162-bp alternative exon that gave rise to two forms, one containing the exon and the other one lacking it. Both forms were found to be coexpressed in a number of selected cell lines and tissue samples. The human EMK1 was shown to be encoded by a single mRNA ubiquitously expressed.

Specifications

• Antigen: Phospho-MARK2 (Thr596)
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: MARK2
• Gene Alias: ELKL motif kinase; ELKL motif kinase 1; Emk; EMK1; EMK-1; MAP/microtubule affinity regulating kinase 2; MAP/microtubule affinity-regulating kinase 2; MARK2; mark2 {ECO:0000312; MGC99619; microtubule affinity regulating kinase 2; OTTHUMP00000218338; OTTHUMP00000218339; OTTHUMP00000218340; OTTHUMP00000218343; Par-1; PAR1 homolog; PAR1 homolog b; Par1b; Par-1b; RGD:708483}; Ser/Thr protein kinase PAR-1B; serine/threonine kinase; serine/threonine protein kinase EMK; serine/threonine-protein kinase MARK2; testicular tissue protein Li 117
• Host Species: Rabbit
• Purification Method: Sequential chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 13728, 2011, 60328
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: O08679, Q05512, Q7KZI7
• Gene Symbols: MARK2
• Immunogen: A synthesized peptide derived from human MARK2(Accession Q7KZI7), corresponding to amino acid residues around phosphorylated Thr596.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov