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Invitrogen™ Phospho-MCM2 (Ser139) Polyclonal Antibody
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Catalog No. PIPA5106185
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PIPA5106185 100 μL
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Catalog No. PIPA5106185 Supplier Invitrogen™ Supplier No. PA5106185
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of MCM2 only when phosphorylated at Ser139.

MCM2 (Mini chromosome maintenance protein 2) is involved in regulating DNA replication. MCM2 (also called CDCL1, mitotin and BM28), is a human nuclear protein that is crucial in the cell cycle, being involved in the onset of DNA replication and cell division. It is similar to members of the family of early S-phase proteins. MCM2 has been mapped to 3q21. From its localization, CDCL1 became a candidate for an oncogene affected by chromosomal breaks in acute myeloid leukemia (AML).
TRUSTED_SUSTAINABILITY

Specifications

Antigen Phospho-MCM2 (Ser139)
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene MCM2
Gene Accession No. P49736, P97310
Gene Alias AA959861; AW476101; BM28; CCNL1; cdc19; CDCL1; cell devision cycle-like 1; cyclin-like 1; D3S3194; DFNA70; DNA replication licensing factor MCM2; Kiaa0030; MCM DNA helicase complex subunit MCM2; Mcm2; Mcmd2; MGC10606; mini chromosome maintenance deficient 2; minichromosome maintenance complex component 2; minichromosome maintenance deficient 2 (mitotin); minichromosome maintenance deficient 2 mitotin; minichromosome maintenance deficient 2 mitotin (S. cerevisiae); Minichromosome maintenance protein 2; Minichromosome maintenance protein 2 homolog; MITOTIN; mKIAA0030; Nuclear protein BM28; YBL023C; YBL0438
Gene Symbols MCM2
Host Species Rabbit
Immunogen A synthesized peptide derived from human MCM2(Accession P49736), corresponding to amino acid residues around phosphorylated Ser139.
Purification Method Sequential chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 17216, 312538, 4171
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

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