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Invitrogen™ Phospho-MEK1/MEK2 (Ser221) Monoclonal Antibody (K.742.1)
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Catalog No. PIMA515118
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100 μL
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Catalog No. Quantity
PIMA515118 100 μL
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Catalog No. PIMA515118 Supplier Invitrogen™ Supplier No. MA515118
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Description

Rabbit Monoclonal Antibody

It is not recommended to aliquot this antibody.

MEK 1 (MAP Kinase Kinase, also known as MKK) is an integral component of the MAP kinase cascade that regulates cell growth and differentiation (Ahn, 1993; Chong et al., 2003). In brain, this pathway also plays a key role in synaptic (Adams and Sweatt, 2002). Activated MEK 1 acts as a dual specificity kinase phosphorylating both a threonine and a tyrosine residue on MAP kinase (Kyriakis et al., 1991; Seger et al., 1991; Crews et al., 1992).
TRUSTED_SUSTAINABILITY

Specifications

Antigen Phospho-MEK1/MEK2 (Ser221)
Applications Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot
Classification Monoclonal
Clone K.742.1
Concentration 246 μg/mL
Conjugate Unconjugated
Formulation 0.01M HEPES with 100μg/mL BSA, 50% glycerol, 0.15M NaCl and <0.02% sodium azide; pH 7.5
Gene MAP2K2
Gene Accession No. P31938, P36506, P36507, Q01986, Q02750, Q1HG70, Q63932
Gene Alias AA589381; CFC3; CFC4; dual specificity mitogen activated protein kinase kinase 1; dual specificity mitogen-activated protein kinase kinase 1; Dual specificity mitogen-activated protein kinase kinase 2; EC 2.7.12.2; ERK activator kinase 1; ERK activator kinase 2; hypothetical protein; hypothetical protein LOC406728; kinase MEK1; MAP kinase kinase 1; MAP kinase kinase 2; MAP kinase/Erk kinase; MAP kinase/Erk kinase 1; Map2k1; Map2k2; MAPK/ERK kinase 1; MAPK/ERK kinase 2; MAPKK 1; MAPKK 2; MAPKK1; MAPKK2; MEK 1; MEK 2; Mek1; MEK-1; Mek2; MEK-2; MEKK1; mitogen activated protein kinase kinase 1; mitogen activated protein kinase kinase 2; mitogen-activated protein kinase kinase 1; mitogen-activated protein kinase kinase 2; mitogen-activated protein kinase kinase 2, p45; mitogen-activated protein kinase kinase type 2; MK2; MKK1; MKK2; MP2K1; PRKMK1; PRKMK2; protein kinase, mitogen activated, kinase 1, p45; protein kinase, mitogen activated, kinase 2, p45; protein kinase, mitogen-activated, kinase 1 (MAP kinase kinase 1); si:ch211-242m18.2; wu:fj56a12; wu:fj61b01; zgc:56557; zgc:56557 protein
Gene Symbols MAP2K1, MAP2K2
Host Species Rabbit
Immunogen Synthetic phosphopeptide corresponding to residues surrounding pSer221 of human MEK1/2.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 170851, 26395, 26396, 478347, 5604, 5605, 58960, 611939
Target Species Human, Mouse, Rat, Canine, Monkey
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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