Phospho-MEK1 (Ser298) Recombinant Rabbit Monoclonal Antibody (MEK1S298-H8), FITC, Invitrogen™

Rabbit Recombinant Monoclonal Antibody

Catalog Number	Mfr. No.	Quantity
PIMA537328	Invitrogen™ MA537328	10 Tests
PIMA537071	Invitrogen™ MA537071	100 Tests

Description

MAP2K1 (MEK1) kinase is a dual-specificity protein kinase that functions in mitogen-activated protein kinase (MAPK) cascades, controlling cell growth and differentiation. MAP2K1 is activated by a wide variety of growth factors and cytokines and also by membrane-dependent depolarization and calcium influx. Mek1 is activated by phosphorylation of serine 218 and 222 residues by Raf1. It is known to be involved in the signaling during stress activate response, apoptosis and proliferative induction by cytokines. Mutations in the gene can lead to cardiofaciocutaneous syndrome.

Specifications

• Antigen: Phospho-MEK1 (Ser298)
• Applications: Flow Cytometry
• Conjugate: FITC
• Host Species: Rabbit
• Target Species: Human, Rat
• Gene Accession No.: Q01986, Q02750
• Gene ID (Entrez): 170851, 5604
• Immunogen: A synthetic phospho-peptide corresponding to residues surrounding Ser298 of human phospho MEK1.
• Primary or Secondary: Primary
• Content And Storage: 4°C, store in dark
• Gene: Map2k1

• Clone: MEK1S298-H8
• Classification: Recombinant Monoclonal
• Form: Liquid
• Regulatory Status: RUO
• Formulation: PBS with 0.20% BSA and 0.09% sodium azide
• Gene Alias: CFC3; dual specificity mitogen activated protein kinase kinase 1; dual specificity mitogen-activated protein kinase kinase 1; EC 2.7.12.2; ERK activator kinase 1; kinase MEK1; MAP kinase kinase 1; MAP kinase kinase or Erk Kinase, Dual specificity mitogen-activated protein kinase kinase, involved in ras mediated vulval induction, LEThal LET-537 (42.8 kD) (mek-2); MAP kinase/Erk kinase 1; Map2k1; map2k1.L; MAPK/ERK kinase 1; MAPKK 1; MAPKK1; MEK 1; Mek1; MEK2; mek-2; MEKK1; mitogen activated protein kinase kinase 1; mitogen-activated protein kinase kinase 1; mitogen-activated protein kinase kinase 1 L homeolog; MKK (Thr292); MKK (Thr386); MKK1; MKK2; MP2K1; Prkmk1; PRKMK2; protein kinase, mitogen activated, kinase 1, p45; protein kinase, mitogen-activated, kinase 1 (MAP kinase kinase 1); XELAEV_18018447mg
• Gene Symbols: Map2k1
• Isotype: IgG κ
• Purification Method: Protein A/G
• Product Type: Antibody