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Invitrogen™ Phospho-MEK1 (Ser298) Recombinant Rabbit Monoclonal Antibody (MEK1S298-H8), PE, Invitrogen™
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Catalog No. PIMA537070
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PIMA537070 100 Tests
PIMA537327 10 Tests
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Catalog No. PIMA537070 Supplier Invitrogen™ Supplier No. MA537070
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Rabbit Recombinant Monoclonal Antibody

MAP2K1 (MEK1) kinase is a dual-specificity protein kinase that functions in mitogen-activated protein kinase (MAPK) cascades, controlling cell growth and differentiation. MAP2K1 is activated by a wide variety of growth factors and cytokines and also by membrane-dependent depolarization and calcium influx. Mek1 is activated by phosphorylation of serine 218 and 222 residues by Raf1. It is known to be involved in the signaling during stress activate response, apoptosis and proliferative induction by cytokines. Mutations in the gene can lead to cardiofaciocutaneous syndrome.
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Specifications

Antigen Phospho-MEK1 (Ser298)
Applications Flow Cytometry
Classification Recombinant Monoclonal
Clone MEK1S298-H8
Conjugate PE
Formulation PBS with 0.20% BSA and 0.09% sodium azide
Gene Map2k1
Gene Accession No. Q02750
Gene Alias CFC3; dual specificity mitogen activated protein kinase kinase 1; dual specificity mitogen-activated protein kinase kinase 1; EC 2.7.12.2; ERK activator kinase 1; kinase MEK1; MAP kinase kinase 1; MAP kinase kinase or Erk Kinase, Dual specificity mitogen-activated protein kinase kinase, involved in ras mediated vulval induction, LEThal LET-537 (42.8 kD) (mek-2); MAP kinase/Erk kinase 1; Map2k1; map2k1.L; MAPK/ERK kinase 1; MAPKK 1; MAPKK1; MEK 1; Mek1; MEK2; mek-2; MEKK1; mitogen activated protein kinase kinase 1; mitogen-activated protein kinase kinase 1; mitogen-activated protein kinase kinase 1 L homeolog; MKK (Thr292); MKK (Thr386); MKK1; MKK2; MP2K1; Prkmk1; PRKMK2; protein kinase, mitogen activated, kinase 1, p45; protein kinase, mitogen-activated, kinase 1 (MAP kinase kinase 1); XELAEV_18018447mg
Gene Symbols Map2k1
Host Species Rabbit
Immunogen A synthetic phosphoo-peptide corresponding to residues surrounding Ser298 of human phospho MEK1.
Purification Method Protein A/G
Quantity 100 Tests
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 5604
Target Species Human
Content And Storage 4°C
Product Type Antibody
Form Liquid
Isotype IgG κ
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