Invitrogen™ Phospho-MEK3/MEK6 (Ser189, Ser207) Recombinant Rabbit Monoclonal Antibody (MKK3S189MKK6S207-D3)

Catalog No.	Quantity
PIMA537054	20 μL
PIMA528041	200 μL

Catalog No. PIMA537054 Supplier Invitrogen™ Supplier No. MA537054

Description

Rabbit Recombinant Monoclonal Antibody

Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.

This gene encodes a member of the dual specificity protein kinase family, which functions as a mitogen-activated protein kinase kinase. MAP kinases, also known as extracellular signal-regulated kinases, act as an integration point for multiple biochemical signals. This protein phosphorylates and activates p38 MAP kinase in response to inflammatory cytokines or environmental stress. As an essential component of p38 MAP kinase mediated signal transduction pathway, this gene is involved in many cellular processes such as stress induced cell cycle arrest, transcription activation and apoptosis.

Specifications

• Antigen: Phospho-MEK3/MEK6 (Ser189, Ser207)
• Applications: Flow Cytometry, Western Blot
• Classification: Recombinant Monoclonal
• Clone: MKK3S189MKK6S207-D3
• Concentration: 0.5 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 0.1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene: MAP2K3
• Gene Accession No.: O09110, P46734, P52564, P70236
• Gene Alias: AW212142; dual specificity mitogen-activated protein kinase kinase 3; Dual specificity mitogen-activated protein kinase kinase 6; MAP kinase kinase 3; MAP kinase kinase 6; Map2k3; Map2k6; MAPK/ERK kinase 3; MAPK/ERK kinase 6; MAPKK 3; MAPKK 6; MAPKK3; MAPKK6; MEK 3; MEK 6; MEK3; MEK6; mitogen activated protein kinase kinase 3; mitogen activated protein kinase kinase 6; mitogen-activated protein kinase kinase 3; mitogen-activated protein kinase kinase 6; MKK3; MKK6; mMKK3b; OTTHUMP00000166044; Prkmk3; Prkmk6; protein kinase, mitogen activated, kinase 6; protein kinase, mitogen-activated, kinase 3; protein kinase, mitogen-activated, kinase 6 (MAP kinase kinase 6); SAPK kinase 2; SAPK kinase 3; SAPKK2; SAPKK-2; SAPKK3; SAPKK-3; SKK2; SKK3; Stress-activated protein kinase kinase 2; stress-activated protein kinase kinase 3
• Gene Symbols: MAP2K3, MAP2K6
• Host Species: Rabbit
• Immunogen: A synthetic phospho-peptide corresponding to residues surrounding Ser189 of human phospho MKK3 and Ser207 of human phospho MKK6.
• Purification Method: Protein A/G
• Quantity: 20 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 26397, 26399, 5606, 5608
• Target Species: Human, Mouse
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG κ

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov