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Invitrogen™ Phospho-MEK3/MEK6 (Ser189, Thr193) Polyclonal Antibody
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Catalog No. PIPA5114603
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PIPA5114603 100 μL
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Catalog No. PIPA5114603 Supplier Invitrogen™ Supplier No. PA5114603
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of MKK3/MKK6 only when phosphorylated at Ser189/Thr193.

This gene encodes a member of the dual specificity protein kinase family, which functions as a mitogen-activated protein kinase kinase. MAP kinases, also known as extracellular signal-regulated kinases, act as an integration point for multiple biochemical signals. This protein phosphorylates and activates p38 MAP kinase in response to inflammatory cytokines or environmental stress. As an essential component of p38 MAP kinase mediated signal transduction pathway, this gene is involved in many cellular processes such as stress induced cell cycle arrest, transcription activation and apoptosis.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Phospho-MEK3/MEK6 (Ser189, Thr193)
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide
Gene MAP2K3
Gene Accession No. O09110, P46734, P52564, P70236
Gene Alias AW212142; dual specificity mitogen-activated protein kinase kinase 3; Dual specificity mitogen-activated protein kinase kinase 6; MAP kinase kinase 3; MAP kinase kinase 6; Map2k3; Map2k6; MAPK/ERK kinase 3; MAPK/ERK kinase 6; MAPKK 3; MAPKK 6; MAPKK3; MAPKK6; MEK 3; MEK 6; MEK3; MEK6; mitogen activated protein kinase kinase 3; mitogen activated protein kinase kinase 6; mitogen-activated protein kinase kinase 3; mitogen-activated protein kinase kinase 6; MKK3; MKK6; mMKK3b; OTTHUMP00000166044; Prkmk3; Prkmk6; protein kinase, mitogen activated, kinase 6; protein kinase, mitogen-activated, kinase 3; protein kinase, mitogen-activated, kinase 6 (MAP kinase kinase 6); SAPK kinase 2; SAPK kinase 3; SAPKK2; SAPKK-2; SAPKK3; SAPKK-3; SKK2; SKK3; Stress-activated protein kinase kinase 2; stress-activated protein kinase kinase 3
Gene Symbols MAP2K3, MAP2K6
Host Species Rabbit
Immunogen A synthesized peptide derived from human MKK3/MKK6 around the phosphorylation site of Ser189/Thr193.
Purification Method sequential chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 114495, 26397, 26399, 303200, 5606, 5608
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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