Invitrogen™ Phospho-MPRIP (Thr542) Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5105059

Catalog No. PIPA5105059

Description

Antibody detects endogenous levels of MRIP only when phosphorylated at Thr542.

Targets myosin phosphatase to the actin cytoskeleton. Required for the regulation of the actin cytoskeleton by RhoA and ROCK1. Depletion leads to an increased number of stress fibers in smooth muscle cells through stabilization of actin fibers by phosphorylated myosin. Overexpression of MRIP as well as its F-actin-binding region leads to disassembly of stress fibers in neuronal cells.

Specifications

• Antigen: Phospho-MPRIP (Thr542)
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: MPRIP
• Gene Alias: 9530046C02; AA536749; AI647711; C76423; KIAA0864; mKIAA0864; Mprip; Mrip; M-RIP; myosin phosphatase Rho interacting protein; myosin phosphatase Rho-interacting protein; myosin phosphatase-Rho interacting protein; p116 Rho interacting protein; p116Rip; Rho interacting protein 3; rho-interacting protein 3; Rho-interacting protein 3 (p116RIP) (RIP3); RHOIP3; RIP3
• Host Species: Rabbit
• Purification Method: Sequential Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 116504, 23164, 26936
• Content And Storage: -20°C
• Form: Liquid

• Applications: Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: P97434, Q6WCQ1, Q9ERE6
• Gene Symbols: MPRIP
• Immunogen: A synthesized peptide derived from human MPRIP(Accession Q6WCQ1), corresponding to amino acid residues around phosphorylated Thr542.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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