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Invitrogen™ Phospho-MRE11 (Ser676) Polyclonal Antibody
Rabbit Polyclonal Antibody
Supplier: Invitrogen™ PA517069
Description
It is not recommended to aliquot this antibody.
MRE11 (double-strand break repair protein MRE11) is a component of the MRN complex. This complex plays a central role in double-strand break repair, DNA recombination, maintenance of telomere integrity and meiosis. The complex possesses single-stranded endonuclease activity and double-strand-specific 3'-5' exonuclease activity which are provided by MRE11. RAD50 is required to bind DNA ends and hold them in close proximity. Mutations in the gene could result in ataxia-telangiectasia-like disorder 1.
Specifications
Phospho-MRE11 (Ser676) | |
Polyclonal | |
Unconjugated | |
Mre11 | |
ATLD; AT-like disease; DNA recombination and repair protein; double-strand break repair protein MRE11; Double-strand break repair protein MRE11A; endo/exonuclease Mre11; HNGS1; Meiotic recombination 11 homolog 1; meiotic recombination 11 homolog A; meiotic recombination 11 homolog A (S. cerevisiae); mmMRE11A; MRE11; MRE11 double strand break repair nuclease A; MRE11 homolog 1; MRE11 homolog A; MRE11 homolog A, double strand break repair nuclease; MRE11 homolog, double strand break repair nuclease; MRE11 homolog, double strand break repair nuclease A; MRE11 meiotic recombination 11 homolog A; MRE11 meiotic recombination 11 homolog A (S. cerevisiae); MRE11 meiotic recombination 11-like protein A; MRE11A; MRE11B; MRX complex nuclease subunit; NGS1; RAD58; XRS4; YM9959.06C; YMR224C | |
Rabbit | |
Antigen affinity chromatography | |
RUO | |
4361 | |
-20°C | |
Liquid |
Western Blot | |
62 μg/mL | |
0.01M HEPES with 100μg/mL BSA, 50% glycerol, 0.15M NaCl and no preservative; pH 7.5 | |
P49959 | |
Mre11 | |
Synthetic peptide corresponding to residues surrounding Ser676 of human Mre11. | |
100 μL | |
Primary | |
Human | |
Antibody | |
IgG |
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