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Phospho-Mre11 (Ser676) Rabbit anti-Human, Polyclonal, Bioss
SDP

Catalog No. 501985283
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50-198-5283 100 μL
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Catalog No. 50-198-5283 Supplier Bioss Supplier No. BS3293R
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Description

Rabbit Polyclonal Antibody

MRE11 (double-strand break repair protein MRE11) is a component of the MRN complex. This complex plays a central role in double-strand break repair, DNA recombination, maintenance of telomere integrity and meiosis. The complex possesses single-stranded endonuclease activity and double-strand-specific 3′-5′ exonuclease activity which are provided by MRE11. RAD50 is required to bind DNA ends and hold them in close proximity. Mutations in the gene could result in ataxia-telangiectasia-like disorder 1.

Specifications

Antigen Phospho-Mre11 (Ser676)
Applications Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 μg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene Mre11
Gene Accession No. P49959
Gene Alias ATLD; AT-like disease; DNA recombination and repair protein; Double-strand break repair protein MRE11; Double-strand break repair protein MRE11A; endo/exonuclease Mre11; HNGS1; Meiotic recombination 11 homolog 1; Meiotic recombination 11 homolog A; meiotic recombination 11 homolog A (S. cerevisiae); MmMRE11A; MRE11; MRE11 double strand break repair nuclease A; MRE11 homolog 1; MRE11 homolog A; MRE11 homolog A, double strand break repair nuclease; MRE11 homolog, double strand break repair nuclease A; MRE11 meiotic recombination 11 homolog A; MRE11 meiotic recombination 11 homolog A (S. cerevisiae); MRE11 meiotic recombination 11-like protein A; Mre11a; MRE11B
Gene Symbols Mre11
Host Species Rabbit
Immunogen KLH conjugated synthetic phosphopeptide derived from rat Mre11 around the phosphorylation site of Ser676.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 4361
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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