Phospho-mTOR (Ser2448) Recombinant Rabbit Monoclonal Antibody (mTORS2448-E11), APC, Invitrogen™

Rabbit Recombinant Monoclonal Antibody

Catalog Number	Mfr. No.	Quantity
PIMA537393	Invitrogen™ MA537393	10 Tests
PIMA537147	Invitrogen™ MA537147	100 Tests

Description

FRAP1 (mTOR) is a serine/threonine kinase that plays a critical role in cellular growth and proliferation. Perturbations in the mTOR/PI3-kinase/AKT pathway are associated with numerous forms of cancer. FRAP1 is also the target of rapamycin and its analogues, which are currently used as immunosuppressants and cancer therapeutics. Mutations affecting the gene results in Smith-Kingsmore syndrome.

Specifications

• Antigen: Phospho-mTOR (Ser2448)
• Applications: Flow Cytometry
• Conjugate: APC
• Host Species: Rabbit
• Target Species: Human, Mouse
• Gene Accession No.: P42345, Q9JLN9
• Gene ID (Entrez): 2475, 56717
• Immunogen: A synthetic phospho-peptide corresponding to residues surrounding Ser2448 of human phospho mTOR.
• Primary or Secondary: Primary
• Content And Storage: 4°C
• Gene: MTOR

• Clone: mTORS2448-E11
• Classification: Recombinant Monoclonal
• Form: Liquid
• Regulatory Status: RUO
• Formulation: PBS with 0.20% BSA and 0.09% sodium azide
• Gene Alias: 2610315D21Rik; AI327068; angiopoietin-like factor CDT6; FK506 binding protein 12-rapamycin associated protein 1; FK506 binding protein 12-rapamycin associated protein 2; FK506-binding protein 12-rapamycin complex-associated protein 1; FKBP12-rapamycin complex-associated protein; FKBP12-rapamycin complex-associated protein 1; FKBP-rapamycin associated protein; FKBP-rapamycin associated protein (FRAP); FKBP-rapamycin-associated protein FRAP; flat; FRAP; FRAP1; FRAP2; Mammalian target of rapamycin; mechanistic target of rapamycin; mechanistic target of rapamycin (serine/threonine kinase); mechanistic target of rapamycin kinase; Mtor; m-TOR; mTORC1; Raft1; Rapamycin and FKBP12 target 1; rapamycin and FKBP12 target-1 protein; rapamycin associated protein FRAP2; rapamycin target protein 1; RAPT1; serine/threonine-protein kinase mTOR; SKS
• Gene Symbols: MTOR
• Isotype: IgG κ
• Purification Method: Protein A/G
• Product Type: Antibody