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Invitrogen™ Phospho-MYL12A (Ser19) Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA126470

Catalog No. PIPA126470


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Description

Description

Recommended positive controls: Cardiac myocytes. PA1-26470 is expected to cross react with all mammals and birds due to 100% sequence homology. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Myosin regulatory light polypeptide 9 is a highly conserved, ubiquitously expressed protein that in humans is encoded by the MYL9 gene. Myosin, a structural component of muscle, are hexameric proteins consisting of two heavy chains and four light chains, including a single pair of nonphosphorylatable light chain subunits and another pair of phosphorylatable light chain subunits.The protein encoded by this gene is a myosin light chain that may regulate muscle contraction by modulating the ATPase activity of myosin heads. Myosin light chain (Myl) 9 and Myl12 are new functional ligands for CD69. Blockade of CD69-Myl9/12 interactio ameliorates allergic airway inflammation in ovalbumin-induced and house dust mite-induced mouse models of asthma.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

Phospho-MYL9/MYL12 (Ser20)
Polyclonal
Unconjugated
MYL12A
1500001M02Rik; 20 kDa myosin light chain; 2900073G15Rik; AI327049; AI838292; brain specific myosin regulatory light chain; C77744; C80200; Epididymis secretory protein Li 24; HEL-S-24; LC20; MLC2; MLC-2; MLC20; MLC-2A; MLC-2B; MLC-2C; MLCB; MLC-B; MRCL3; MRLC1; Mrlc2; MRLC3; Mrlcb; Myl12a; MYL12B; MYL2B; MYL9; MYLC2B; Mylc2c; myosin light chain 12A; myosin light chain 12B; myosin light chain 9; myosin light chain, regulatory B; myosin light chain, regulatory B-like; myosin light chain, regulatory C; myosin regulatory light chain 1; myosin regulatory light chain 12A; Myosin regulatory light chain 12B; myosin regulatory light chain 2; myosin regulatory light chain 2, nonsarcomeric; Myosin regulatory light chain 2, smooth muscle isoform; myosin regulatory light chain 20 kDa; myosin regulatory light chain 2-A, smooth muscle isoform; Myosin regulatory light chain 2-B, smooth muscle isoform; myosin regulatory light chain 3; myosin regulatory light chain 9; Myosin regulatory light chain MRLC1; myosin regulatory light chain MRLC2; Myosin regulatory light chain MRLC3; myosin regulatory light chain RLC-A; myosin regulatory light chain-B; myosin regulatory light polypeptide 9; Myosin RLC; myosin RLC-A; Myosin RLC-B; myosin, light chain 12A, regulatory, non-sarcomeric; myosin, light chain 12B, regulatory; myosin, light chain 9, regulatory; myosin, light polypeptide 9, regulatory; myosin, light polypeptide, regulatory, non-sarcomeric (20kD); MYRL2; NMDA receptor-interacting protein; RGD1309537; RLC; Rlc-a; RLC-B; RLC-C; SHUJUN-1
Rabbit
Antigen affinity chromatography
RUO
103910, 10398, 10627, 67268, 67938, 98932
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Liquid
ELISA, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot, Immunocytochemistry
1.19 mg/mL
0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2
O14950, P19105, P24844, Q3THE2, Q9CQ19
MYL12A, MYL12B, MYL9
Synthetic phosphopeptide corresponding to residues K(12) K R P Q R A T (pS) N V F A M F D(27) of the human Myosin Light Chain protein.
50 μg
Primary
Human, Mouse
Antibody
IgG
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