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Invitrogen™ Phospho-MYL12A (Ser19) Polyclonal Antibody
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Catalog No. PIPA126470
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50 μg
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PIPA126470 50 μg
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Catalog No. PIPA126470 Supplier Invitrogen™ Supplier No. PA126470
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Description

Rabbit Polyclonal Antibody

Recommended positive controls: Cardiac myocytes. PA1-26470 is expected to cross react with all mammals and birds due to 100% sequence homology. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

This gene encodes a nonsarcomeric myosin regulatory light chain. This protein is activated by phosphorylation and regulates smooth muscle and non-muscle cell contraction. This protein may also be involved in DNA damage repair by sequestering the transcriptional regulator apoptosis-antagonizing transcription factor (AATF)/Che-1 which functions as a repressor of p53-driven apoptosis. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 8.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Phospho-MYL12A (Ser19)
Applications ELISA, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1.19 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.15M NaCl and 0.01% sodium azide; pH 7.2
Gene Myl12a
Gene Accession No. P19105
Gene Alias 2900073G15Rik; AI838292; brain specific myosin regulatory light chain; C80200; Epididymis secretory protein Li 24; HEL-S-24; MLC-2; MLC20; MLC-2A; MLC-2B; MLCB; MRCL3; MRLC2; MRLC3; MYL12A; MYL12B; MYL2B; MYLC2B; myosin light chain 12A; myosin light chain, regulatory B-like; myosin regulatory light chain 12A; Myosin regulatory light chain 12B; Myosin regulatory light chain 2, nonsarcomeric; Myosin regulatory light chain 20 kDa; myosin regulatory light chain 2-A, smooth muscle isoform; Myosin regulatory light chain 2-B, smooth muscle isoform; myosin regulatory light chain 3; Myosin regulatory light chain MRLC2; Myosin regulatory light chain MRLC3; myosin regulatory light chain RLC-A; Myosin RLC; myosin RLC-A; myosin, light chain 12A, regulatory, non-sarcomeric; myosin, light polypeptide, regulatory, non-sarcomeric (20kD); NMDA receptor-interacting protein; RGD1309537; RLC; Rlc-a; SHUJUN-1
Gene Symbols Myl12a
Host Species Rabbit
Immunogen Human Myosin Light Chain phospho peptide corresponding to a region near the amino terminus of the human smooth/non-muscle form of myosin regulatory light chain conjugated to KLH.
Purification Method Antigen affinity chromatography
Quantity 50 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10627, 67268
Target Species Human, Mouse
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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