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Invitrogen™ Phospho-NACA (Thr159) Polyclonal Antibody
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Catalog No. PIPA564694
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PIPA564694 100 μL
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Catalog No. PIPA564694 Supplier Invitrogen™ Supplier No. PA564694
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Description

Rabbit Polyclonal Antibody

Phospho-NACA (Thr159) Polyclonal Antibody detects endogenous levels of NACA only when phosphorylated at Thr159.

NACA prevents inappropriate targeting of non-secretory polypeptides to the endoplasmic reticulum (ER). It binds to nascent polypeptide chains as they emerge from the ribosome and blocks their interaction with the signal recognition particle (SRP), which normally targets nascent secretory peptides to the ER. NACA also reduces the inherent affinity of ribosomes for protein translocation sites in the ER membrane (M sites), and may act as a specific coactivator for JUN, binding to DNA and stabilizing the interaction of JUN homodimers with target gene promoters.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Phospho-NACA (Thr159)
Applications Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene NACA
Gene Accession No. E9PAV3, P70670, Q13765, Q60817
Gene Alias AL022831; AL024382; Alpha-NAC; Alpha-NAC, muscle-specific form; alpha-NAC/1.9.2; Gm1878; Hom s 2; HSD48; mKIAA0363; NACA; NACA1; NAC-alpha; nascent polypeptide-associated complex alpha polypeptide; nascent polypeptide-associated complex alpha subunit; nascent polypeptide-associated complex subunit alpha; Nascent polypeptide-associated complex subunit alpha, muscle-specific form; nascent-polypeptide-associated complex alpha polypeptide; skNAC
Gene Symbols NACA
Host Species Rabbit
Immunogen A synthesized peptide derived from human NACA (Phospho-Thr159).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 17938, 288770, 4666
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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