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Invitrogen™ Phospho-NBS1 (Ser343) Polyclonal Antibody
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Catalog No. PIPA5104706
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100 μL
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PIPA5104706 100 μL
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Catalog No. PIPA5104706 Supplier Invitrogen™ Supplier No. PA5104706
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of p95/NBS1 only when phosphorylated at Serine 343.

The p95 gene (identical to NBS1 and nibrin) is a member of the hMre11/hRad50 double-strand break complex. This protein complex has been implicated in Nijmegen breakage syndrome, an autosomal recessive disorder marked by increased cancer incidence, cell cycle checkpoint deficits, and ionizing radiation sensitivity, thus revealing a direct molecular link between double-strand break repair and cell cycle checkpoint functions.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Phospho-NBS1 (Ser343)
Applications Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene NBN
Gene Accession No. O60934, Q9JIL9, Q9R207
Gene Alias AT V1; AT V2; ATV; AT-V1; AT-V2; Cell cycle regulatory protein p95; FLJ10155; I79_012607; MGC87362; Nbn; NBS; NBS1; nibrin; Nijmegen breakage syndrome 1 (nibrin); Nijmegen breakage syndrome protein 1; Nijmegen breakage syndrome protein 1 homolog; OTTHUMP00000204088; P95; p95 protein of the MRE11/RAD50 complex; p95-NBS1
Gene Symbols NBN
Host Species Rabbit
Immunogen A synthesized peptide derived from human NBN(Accession O60934), corresponding to amino acid residues around phosphorylated Ser343.
Purification Method Sequential Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 27354, 4683, 85482
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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