Invitrogen™ Phospho-NBS1 (Ser343) Recombinant Rabbit Monoclonal Antibody (1B4)

Rabbit Recombinant Monoclonal Antibody

Supplier:  Invitrogen™ MA533184

Catalog No. PIMA533184

Description

Phospho-NBS1 (Ser343) Recombinant Monoclonal Antibody for Western Blot, ELISA

The p95 gene (identical to NBS1 and nibrin) is a member of the hMre11/hRad50 double-strand break complex. This protein complex has been implicated in Nijmegen breakage syndrome, an autosomal recessive disorder marked by increased cancer incidence, cell cycle checkpoint deficits, and ionizing radiation sensitivity, thus revealing a direct molecular link between double-strand break repair and cell cycle checkpoint functions.

Specifications

• Antigen: Phospho-NBS1 (Ser343)
• Classification: Recombinant Monoclonal
• Concentration: 2.5 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: O60934
• Gene Symbols: NBN
• Immunogen: A synthesized peptide derived from human Phospho-NBN (S343).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

• Applications: ELISA, Western Blot
• Clone: 1B4
• Conjugate: Unconjugated
• Gene: NBN
• Gene Alias: AT V1; AT V2; ATV; AT-V1; AT-V2; Cell cycle regulatory protein p95; FLJ10155; I79_012607; MGC87362; Nbn; NBS; NBS1; nibrin; Nijmegen breakage syndrome 1 (nibrin); Nijmegen breakage syndrome protein 1; Nijmegen breakage syndrome protein 1 homolog; OTTHUMP00000204088; P95; p95 protein of the MRE11/RAD50 complex; p95-NBS1
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography, Protein G
• Regulatory Status: RUO
• Gene ID (Entrez): 4683
• Content And Storage: -20°C or -80°C if preferred
• Form: Liquid