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Phospho-NEDD4L (Ser342) Rabbit anti-Human, Polyclonal, Bioss Non-distribution product as customer accommodation.

Rabbit Polyclonal Antibody

Manufacturer:  BiossSupplier Diversity Partner BS3299R

Catalog No. 50-198-5288


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Description

Description

NEDD4L is an E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. NEDD4L inhibits TGF-beta signaling by triggering SMAD2 and TGFR1 ubiquitination and proteasome-dependent degradation. NEDD4L promotes ubiquitination and internalization of various plasma membrane channels such as ENaC, Nav1.2, Nav1.3, Nav1.5, Nav1.7, Nav1.8, Kv1.3, EAAT1 or CLC5. NEDD4L also promotes ubiquitination and degradation of SGK.
Specifications

Specifications

Phospho-NEDD4L (Ser342)
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Unconjugated
NEDD4L
Liquid
Rabbit
IgG
100 μL
-20°C
Primary
23327
NEDD4L
1 μg/mL
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Q96PU5
1300012C07Rik; BOS_22342; E3 ubiquitin-protein ligase NEDD4-like; FLJ33870; HECT-type E3 ubiquitin transferase NED4L; hNEDD4-2; KIAA0439; NEDD4; NEDD4.2; Nedd4-2; Nedd4b; NEDD4L; NEDL3; neural precursor cell expressed, developmentally down-regulated 4-like; neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase; neural precursor cell expressed, developmentally down-regulated gene 4b; neural precursor cell expressed, developmentally down-regulated gene 4-like; RSP5; ubiquitin-protein ligase Nedd4-2; ubiquitin-protein ligase Rsp5
KLH conjugated synthetic phosphopeptide derived from human NEDD4L around the phosphorylation site of Ser342.
Protein A
RUO
Antibody
Polyclonal
Human
SDS
Documents
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