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Invitrogen™ Phospho-NF2 (Ser518) Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA517072

Catalog No. PIPA517072


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Description

Description

It is not recommended to aliquot this antibody.

NF2 encodes a protein, Merlin, that is similar to some members of the ERM family of proteins that are thought to link cytoskeletal components with proteins in the cell membrane. Merlin has been shown to interact with cell-surface proteins, proteins involved in cytoskeletal dynamics and proteins involved in regulating ion transport. This gene is expressed at high levels during embryonic development; in adults, significant expression is found in Schwann cells, meningeal cells, lens and nerve. Mutations in this gene are associated with neurofibromatosis type II which is characterized by nervous system and skin tumors and ocular abnormalities. Two predominant isoforms and a number of minor isoforms are produced by alternatively spliced transcripts.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

Phospho-NF2 (Ser518)
Polyclonal
0.01M HEPES with 100μg/mL BSA, 50% glycerol, 0.15M NaCl and no preservative; pH 7.5
P35240, P46662, Q63648
Nf2
Synthetic peptide corresponding to the sequence of human merlin.
100 μL
Primary
Human, Mouse, Rat, Monkey
Antibody
IgG
Immunoprecipitation, Western Blot
Unconjugated
Nf2
ACN; BANF; Merlin; MGC123124; moesin-ezrin-radixin like; moesin-ezrin-radixin-like protein; moesin-ezrin-radizin-like protein; neurofibromatosis 2; neurofibromin 2; neurofibromin 2 (bilateral acoustic neuroma); neurofibromin 2 (merlin); neurofibromin 2b (merlin); neurofibromin-2; Nf2; Nf-2; NF2a; nf2b; OTTHUMP00000199607; SCH; Schwannomerlin; schwannomin
Rabbit
Antigen affinity chromatography
RUO
18016, 25744, 4771
-20°C
Liquid
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