Phospho-NFAT5 (Ser1197) Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Supplier:  Thermo Scientific PA538884

Catalog No. PIPA538884

Description

The nuclear factor of activated T-cells (NFAT) transcription complex is required for the expression of a group of proteins that collectively regulate the immune response. Four NFAT proteins, encoded on separate genes and expressed as several splice variants, have been described: NFAT1 (also known as NFATp or NFATc2), NFAT2 (NFATc or NFATc1), NFAT3, and NFAT4 (NFATx or NFATc3). These proteins show a low level of sequence similarity with the Dorsal/Rel/NFkB family of transcription factors. Another NFAT-related protein termed NFAT5 differs from isoforms 1-4 in that it lacks many of the Fos/Jun contact sites observed in its predecessors and its subcellular localization is not calcineurin-dependent.

Specifications

• Antigen: Phospho-NFAT5 (Ser1197)
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: NFAT5
• Gene Alias: Nuclear Factor Activated T-Cells, NFATL1, Nuclear factor of activated T cells 5, T cell transcription factor NFAT5, NF-AT5, Tonicity-responsive enhanc
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 10725, 54446
• Content And Storage: -20°C
• Form: Liquid

• Applications: Peptide ELISA, Immunofluorescence
• Concentration: 1 mg/mL
• Formulation: Dulbecco′s PBS with 150mM NaCl, 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: O94916, Q9WV30
• Gene Symbols: NFAT5
• Immunogen: A synthetic phosphopeptide derived from human NFAT5 around the phosphorylation site of Ser1197 (M-L-SP-Q-E)
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Non-human Primate
• Product Type: Antibody
• Isotype: IgG