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Invitrogen™ Phospho-NFATC1 (Ser172) Polyclonal Antibody
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Catalog No. PIPA564696
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PIPA564696 100 μL
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Catalog No. PIPA564696 Supplier Invitrogen™ Supplier No. PA564696
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Description

Rabbit Polyclonal Antibody

Phospho-NFATC1 (Ser172) Polyclonal Antibody detects endogenous levels of NFATC1 only when phosphorylated at Ser172.

The product of this gene is a component of the nuclear factor of activated T cells DNA-binding transcription complex. This complex consists of at least two components: a preexisting cytosolic component that translocates to the nucleus upon T cell receptor (TCR) stimulation, and an inducible nuclear component. Proteins belonging to this family of transcription factors play a central role in inducible gene transcription during immune response. The product of this gene is an inducible nuclear component. It functions as a major molecular target for the immunosuppressive drugs such as cyclosporin A. Five transcript variants encoding distinct isoforms have been identified for this gene. Different isoforms of this protein may regulate inducible expression of different cytokine genes.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Phospho-NFATC1 (Ser172)
Applications Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol, 0.5% BSA and 0.02% sodium azide; pH 7.4
Gene NFATC1
Gene Accession No. O88942, O95644
Gene Alias 2210017P03Rik; AI449492; AV076380; MGC138448; NFAT tra; NFAT trans; NFAT transcription complex cytosolic component; NFAT2; NFATc; NF-ATC; NFATC1; NF-ATc1; NF-ATc1.2; Nfatcb; nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 1; nuclear factor of activated T-cells 1; nuclear factor of activated T-cells 'c'; nuclear factor of activated T-cells, cytoplasmic 1; nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1; transcription factor NF-ATc
Gene Symbols NFATC1
Host Species Rabbit
Immunogen A synthesized peptide derived from human NFAT2 (Phospho-Ser172).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 18018, 4772
Target Species Human, Mouse
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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