Invitrogen™ Phospho-NFATC3 (Ser165) Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5104980

Catalog No. PIPA5104980

Description

Antibody detects endogenous levels of NFAT4 only when phosphorylated at Serine 165.

This gene encodes a protein that is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense-mediated mRNA decay (NMD). When translation ends upstream from the last exon-exon junction, this triggers NMD to degrade mRNAs containing premature stop codons. This protein is located only in the cytoplasm. When translation ends, it interacts with the protein that is a functional homolog of yeast Upf2p to trigger mRNA decapping. Use of multiple polyadenylation sites has been noted for this gene.

Specifications

• Antigen: Phospho-NFATC3 (Ser165)
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: NFATC3
• Gene Alias: C80703; D8Ertd281e; NFAC3; NFAT4; NF-AT4; NFATC3; NF-ATc3; NFATx; NFC3; nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 3; nuclear factor of activated T-cells 3; nuclear factor of activated T-cells c3 isoform IE-Xa; nuclear factor of activated T-cells, cytoplasmic 3; nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3; T cell transcription factor NFAT4; T-cell transcription factor NFAT4
• Host Species: Rabbit
• Purification Method: Sequential Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 18021, 361400, 4775
• Content And Storage: -20°C
• Form: Liquid

• Applications: Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: P97305, Q12968
• Gene Symbols: NFATC3
• Immunogen: A synthesized peptide derived from human NFATC3(Accession Q12968), corresponding to amino acid residues around phosphorylated Ser165.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG