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Invitrogen™ Phospho-NFkB p100 (Ser866) Polyclonal Antibody
Rabbit Polyclonal Antibody
Supplier: Invitrogen™ PA5121273
This item is not returnable.
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Description
Positive test controls include: ovary cancer. The target is usually found in the following locations: Cytoplasm, Nucleus. Immunogen sequence: EDSAY.
This gene encodes a subunit of the transcription factor complex nuclear factor-kappa-B (NFkB). The NFkB complex is expressed in numerous cell types and functions as a central activator of genes involved in inflammation and immune function. The protein encoded by this gene can function as both a transcriptional activator or repressor depending on its dimerization partner. The p100 full-length protein is co-translationally processed into a p52 active form. Chromosomal rearrangements and translocations of this locus have been observed in B cell lymphomas, some of which may result in the formation of fusion proteins. There is a pseudogene for this gene on chromosome 18. Alternative splicing results in multiple transcript variants.
Specifications
Phospho-NFkB p100 (Ser866) | |
Polyclonal | |
Unconjugated | |
Nfkb2 | |
CVID10; DNA-binding factor KBF2; H2TF1; Lymphocyte translocation chromosome 10 protein; lyt; Lyt10; LYT-10; NF kappaB2; NF-kappaB2; NF-kB p100; NFKB, p52/p100 subunit; NFKB2; NF-kB2; nuclear factor kappa B subunit 2; nuclear factor Kappa-B, subunit 2; nuclear factor NF-kappa-B p100 subunit; Nuclear factor NF-kappa-B p52 subunit; nuclear factor of Kappa light chain gene enhancer in B cells 2; nuclear factor of kappa light polypeptide gene enhancer in B cells 2, p49/p100; Nuclear factor of kappa light polypeptide gene enhancer in B-cells 2; nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100); nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100; oncogene Lyt-10; p100; p49; p49/p100; p50B; p52; RGD1307189; transcription factor NFKB2 | |
Rabbit | |
Affinity chromatography | |
RUO | |
18034, 4791 | |
-20°C, Avoid Freeze/Thaw Cycles | |
Liquid |
ELISA, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry | |
0.71 mg/mL | |
PBS with 50% glycerol and 0.01% thimerosal; pH 7.3 | |
Q00653, Q9WTK5 | |
Nfkb2 | |
A synthetic phosphorylated peptide around S866 of human NF-?B2 (NP_0010709621). | |
100 μL | |
Primary | |
Human, Mouse | |
Antibody | |
IgG |
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