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Invitrogen™ Phospho-NFkB p52/p100 (Ser870) Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5104947

Catalog No. PIPA5104947


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Description

Description

Antibody detects endogenous levels of NF kappaB p100/p52 only when phosphorylated at Serine 870.

The NFkB transcription factor was originally identified as a protein complex consisting of a DNA binding subunit and an associated protein. The subunit is functionally related to c-Rel p75 and Rel B p68. The p50 subunit was initially believed to be a functionally unique protein derived from the amino-terminus of a precursor designated p105. A cDNA has been isolated that encodes an alternative DNA binding subunit of NFkB. It is synthesized as a protein that is expressed in a variety of cell types and, like p105, undergoes cleavage to generate its NFkB subunit, in this case a protein designated p52 (previously referred to as p49). In contrast to p50 derived from p105, p52 acts in synergy with p65 to stimulate the HIV enhancer in transiently transfected Jurkat cells.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

Phospho-NFkB p52/p100 (Ser870)
Polyclonal
Unconjugated
Nfkb2
CVID10; DNA-binding factor KBF2; H2TF1; Lymphocyte translocation chromosome 10 protein; lyt; LYT10; LYT-10; NF kappaB2; NF KB; NF-kappaB2; nfkb p100; NF-kB p52/p100; NFKB, p52/p100 subunit; NFKB2; NF-kB2; nuclear factor; nuclear factor kappa b; nuclear factor kappa B subunit 2; nuclear factor Kappa-B, subunit 2; nuclear factor NF-kappa-B p100 subunit; Nuclear factor NF-kappa-B p52 subunit; nuclear factor of Kappa light chain gene enhancer in B cells 2; nuclear factor of kappa light polypeptide gene enhancer in B cells 2, p49/p100; Nuclear factor of kappa light polypeptide gene enhancer in B-cells 2; nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100); nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100; oncogene Lyt-10; p100; p49; p49/p100; p50B; p52; RGD1307189; transcription factor NFKB2
Rabbit
Sequential Chromatography
RUO
18034, 309452, 4791
-20°C
Liquid
Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot, Immunocytochemistry
1 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Q00653, Q9WTK5
Nfkb2
A synthesized peptide derived from human NFKB2(Accession Q00653), corresponding to amino acid residues around phosphorylated Ser870.
100 μL
Primary
Human, Mouse, Rat
Antibody
IgG
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