Invitrogen™ Phospho-NMDAR2C (Ser1244) Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA535403

Catalog No. PIPA535403

Description

This antibody is predicted to react with bovine and canine based on 100% sequence homology. This antibody contains enough material to conduct 10 mini-Western blots.

The NMDA Receptor (NMDAR) plays an essential role in memory, neuronal development and it has also been implicated in several disorders of the central nervous system including Alzheimers, epilepsy and ischemic neuronal cell death. The NMDA receptor is also one of the principal molecular targets for alcohol in the CNS. The NMDAR is also potentiated by protein phosphorylation. The NR1 protein can form NMDA activated channels when expressed in Xenopus oocytes but the currents in such channels are much smaller than those seen in situ. Channels with more physiological characteristics are produced when the NR1 subunit is combined with one or more of th NMDAR2 (NR2 A-D) subunits.

Specifications

• Antigen: Phospho-NMDAR2C (Ser1244)
• Classification: Polyclonal
• Formulation: 0.01M HEPES with 0.1mg/mL BSA, 50% glycerol, 0.15M NaCl and no preservative; pH 7.5
• Gene Accession No.: Q00961, Q01098
• Gene Symbols: GRIN2C
• Immunogen: Synthetic phospho-peptide corresponding to amino acid residues surrounding Ser1244 of rat GRIN2C conjugated to KLH.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

• Applications: Western Blot
• Conjugate: Unconjugated
• Gene: GRIN2C
• Gene Alias: GluN2C; GluRepsilon3; glutamate [NMDA] receptor subunit epsilon-3; glutamate ionotropic receptor NMDA type subunit 2C; glutamate receptor; glutamate receptor ionotropic, NMDA 2C; glutamate receptor ionotropic, NMDA 2C; LOW QUALITY PROTEIN: glutamate receptor ionotropic, NMDA 2C; glutamate receptor, ionotropic, NMDA2C; glutamate receptor, ionotropic, NMDA2C (epsilon 3); glutamate receptor, ionotropic, N-methyl D-aspartate 2C; Grin2c; LOW QUALITY PROTEIN: glutamate receptor ionotropic, NMDA 2C; NMDA glutamate receptor; NMDAR2C; N-methyl D-aspartate receptor subtype 2C; N-methyl-D-aspartate receptor subunit 2C; NR2; NR2C
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 14813, 24411
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov