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Invitrogen™ Phospho-NMDAR2C (Ser1244) Polyclonal Antibody
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Catalog No. PIPA535403
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PIPA535403 100 μL
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Catalog No. PIPA535403 Supplier Invitrogen™ Supplier No. PA535403
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Description

Rabbit Polyclonal Antibody

This antibody is predicted to react with bovine and canine based on 100% sequence homology. This antibody contains enough material to conduct 10 mini-Western blots.

The NMDA Receptor (NMDAR) plays an essential role in memory, neuronal development and it has also been implicated in several disorders of the central nervous system including Alzheimers, epilepsy and ischemic neuronal cell death. The NMDA receptor is also one of the principal molecular targets for alcohol in the CNS. The NMDAR is also potentiated by protein phosphorylation. The NR1 protein can form NMDA activated channels when expressed in Xenopus oocytes but the currents in such channels are much smaller than those seen in situ. Channels with more physiological characteristics are produced when the NR1 subunit is combined with one or more of th NMDAR2 (NR2 A-D) subunits.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Phospho-NMDAR2C (Ser1244)
Applications Western Blot
Classification Polyclonal
Concentration 0.25 mg/mL
Conjugate Unconjugated
Formulation 0.01M HEPES with 0.1mg/mL BSA, 50% glycerol, 0.15M NaCl and no preservative; pH 7.5
Gene GRIN2C
Gene Accession No. Q00961, Q01098
Gene Alias GluN2C; GluRepsilon3; glutamate [NMDA] receptor subunit epsilon-3; glutamate ionotropic receptor NMDA type subunit 2C; glutamate receptor; glutamate receptor ionotropic, NMDA 2C; glutamate receptor ionotropic, NMDA 2C; LOW QUALITY PROTEIN: glutamate receptor ionotropic, NMDA 2C; glutamate receptor, ionotropic, NMDA2C; glutamate receptor, ionotropic, NMDA2C (epsilon 3); glutamate receptor, ionotropic, N-methyl D-aspartate 2C; Grin2c; LOW QUALITY PROTEIN: glutamate receptor ionotropic, NMDA 2C; NMDA glutamate receptor; NMDAR2C; N-methyl D-aspartate receptor subtype 2C; N-methyl-D-aspartate receptor subunit 2C; NR2; NR2C
Gene Symbols GRIN2C
Host Species Rabbit
Immunogen Synthetic phospho-peptide corresponding to amino acid residues surrounding Ser1244 of rat GRIN2C conjugated to KLH.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 14813, 24411
Target Species Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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